ATCTH Zinc finger C-x8-C-x5-C-x3-H type family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ATCTH
Official Full Name: Zinc finger C-x8-C-x5-C-x3-H type family protein
Primary source: TAIR:AT2G25900
Locus tag: AT2G25900
See related: Araport:AT2G25900
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: A. THALIANA TANDEM ZINC FINGER PROTEIN 1; ATTZF1; F17H15.7; F17H15_7; PUTATIVE CYS3HIS ZINC FINGER PROTEIN
Summary: putative Cys3His zinc finger protein (ATCTH) mRNA, complete
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Genomic context

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See ATCTH in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 2

Sequence:: Chromosome: 2; NC_003071.7 (11041331..11043256)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Findings suggest that Pseudo Response Regulators (PRRs)- Tandem Zinc Finger 1 (TZF1)- Target Of Rapamycin (TOR) signaling modulates root meristem cell proliferation by integrating both transcriptional and post-transcriptional regulatory mechanisms.
Title: PRR5, 7 and 9 positively modulate TOR signaling-mediated root cell proliferation by repressing TANDEM ZINC FINGER 1 in Arabidopsis.
AtTZF1 triggers the decay of AU-rich elements-containing mRNAs.TFZ1 protein zinc finger integrity is vital for RNA binding.
Title: The Arabidopsis thaliana tandem zinc finger 1 (AtTZF1) protein in RNA binding and decay.
Overexpression of AtZFP1 enhances salt tolerance by maintaining ionic balance and limiting oxidative and osmotic stress.
Title: The CCCH zinc finger protein gene AtZFP1 improves salt resistance in Arabidopsis thaliana.
AtTZF1 may serve as a regulator connecting sugar, ABA, GA and peptide hormone responses.
Title: The Arabidopsis tandem zinc finger protein AtTZF1 affects ABA- and GA-mediated growth, stress and gene expression responses.
AtTZF1 fusion proteins could not exert obvious transcriptional activity in a maize protoplast transient expression system.
Title: Can AtTZF1 act as a transcriptional activator or repressor in plants?
This study suggested that, Since TZF1 can bind both DNA and RNA in vitro, it raises the possibility that TZF1 might be involved in DNA and/or RNA regulation.
Title: The Arabidopsis tandem zinc finger protein AtTZF1 traffics between the nucleus and cytoplasmic foci and binds both DNA and RNA.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001202675.1

Supported by ESTs:

NM_128150.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA binding	IDA Inferred from Direct Assay more info	PubMed
enables single-stranded RNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA destabilization	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Zinc finger C-x8-C-x5-C-x3-H type family protein

NP_001189604.1

ATCTH; CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571); BEST Arabidopsis thaliana protein match is: CCCH-type zinc finger family protein (TAIR:AT2G19810.1).

NP_180161.1

ATCTH; CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571); BEST Arabidopsis thaliana protein match is: CCCH-type zinc finger family protein (TAIR:AT2G19810.1); Has 796 Blast hits to 771 proteins in 136 species: Archae - 0; Bacteria - 0; Metazoa - 198; Fungi - 6; Plants - 407; Viruses - 0; Other Eukaryotes - 185 (source: NCBI BLink).