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    SAG13 senescence-associated gene 13 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817484, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SAG13
    Official Full Name
    senescence-associated gene 13
    Primary source
    TAIR:AT2G29350
    Locus tag
    AT2G29350
    See related
    Araport:AT2G29350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CI0011; F16P2.27; F16P2_27; senescence-associated gene 13
    Summary
    senescence-associated gene SAG13 encoding a short-chain alcohol dehydrogenase
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    Genomic context

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    See SAG13 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (12600914..12602556)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene tropinone reductase Neighboring gene NAD-dependent epimerase/dehydratase family protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis SENESCENCE-ASSOCIATED GENE 13 Regulates Dark-Induced Senescence and Plays Contrasting Roles in Defense Against Bacterial and Fungal Pathogens. Dhar N, et al. Mol Plant Microbe Interact, 2020 May. PMID 32065029
    2. Antibiosis against the green peach aphid requires the Arabidopsis thaliana MYZUS PERSICAE-INDUCED LIPASE1 gene. Louis J, et al. Plant J, 2010 Dec. PMID 21105927
    3. Effects of cytokinin production under two SAG promoters on senescence and development of tomato plants. Swartzberg D, et al. Plant Biol (Stuttg), 2006 Sep. PMID 16883480
    4. Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense. Brodersen P, et al. Genes Dev, 2002 Feb 15. PMID 11850411, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036365.1
    NM_128489.3
    NM_201829.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alcohol dehydrogenase (NAD+) activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to insect IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    senescence-associated gene 13
    NP_001031442.1
    • senescence-associated gene 13 (SAG13); CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT2G29290.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_180496.1
    • senescence-associated gene 13 (SAG13); CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT2G29290.2); Has 124599 Blast hits to 124224 proteins in 3643 species: Archae - 998; Bacteria - 81817; Metazoa - 5872; Fungi - 6443; Plants - 2971; Viruses - 5; Other Eukaryotes - 26493 (source: NCBI BLink).
    NP_973558.1
    • senescence-associated gene 13 (SAG13); CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT2G29290.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12600914..12602556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_201829.2 → NP_973558.1  senescence-associated gene 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973558.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW18
      Conserved Domains (2) summary
      pfam00106
      Location:19 → 211
      adh_short; short chain dehydrogenase
      cl21454
      Location:12 → 204
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. NM_128489.3 → NP_180496.1  senescence-associated gene 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180496.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IKM5, F4IKM6, Q9ZW18
      UniProtKB/TrEMBL
      A0A178VTS8, A0A5S9X297, Q9SP04
      Conserved Domains (1) summary
      cl21454
      Location:12 → 261
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. NM_001036365.1 → NP_001031442.1  senescence-associated gene 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031442.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW18
      Conserved Domains (2) summary
      PRK07677
      Location:2 → 227
      PRK07677; short chain dehydrogenase; Provisional
      cl21454
      Location:2 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZW18.1

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