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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842691, updated on 18-Sep-2024

    Summary

    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT1G63870
    Locus tag
    AT1G63870
    See related
    Araport:AT1G63870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T12P18.11; T12P18_11
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (23707131..23711944, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene E3 Ubiquitin ligase family protein

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_176571.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane, chloroplast; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT1G63880.1); Has 19720 Blast hits to 15752 proteins in 683 species: Archae - 12; Bacteria - 1411; Metazoa - 1255; Fungi - 60; Plants - 16579; Viruses - 2; Other Eukaryotes - 401 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23707131..23711944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105061.2NP_176571.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176571.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WRX4, Q9CAK0
      Conserved Domains (5) summary
      PLN03210
      Location:6999
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:603625
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:17182
      TIR; TIR domain
      pfam07725
      Location:602621
      LRR_3; Leucine Rich Repeat
      pfam13191
      Location:191311
      AAA_16; AAA ATPase domain