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    N2,N2-dimethylguanosine tRNA methyltransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820451, updated on 18-Sep-2024

    Summary

    Official Full Name
    N2,N2-dimethylguanosine tRNA methyltransferase
    Primary source
    TAIR:AT3G02320
    Locus tag
    AT3G02320
    See related
    Araport:AT3G02320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F11A12.1; F11A12_1
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    Genomic context

    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (469867..473717)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene K-box region and MADS-box transcription factor family protein Neighboring gene tRNA-Ile Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene tRNA-Asp

    General gene information

    NM_111099.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables tRNA (guanine(10)-N2)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA (guanine(26)-N2)-dimethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA modification IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    N2,N2-dimethylguanosine tRNA methyltransferase
    NP_186881.2
    • N2,N2-dimethylguanosine tRNA methyltransferase; FUNCTIONS IN: RNA binding, tRNA (guanine-N2-)-methyltransferase activity; INVOLVED IN: tRNA processing; LOCATED IN: cellular_component unknown; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: N2,N2-dimethylguanosine tRNA methyltransferase (InterPro:IPR002905); BEST Arabidopsis thaliana protein match is: N2,N2-dimethylguanosine tRNA methyltransferase (TAIR:AT5G15810.1); Has 1019 Blast hits to 973 proteins in 363 species: Archae - 257; Bacteria - 68; Metazoa - 198; Fungi - 156; Plants - 105; Viruses - 0; Other Eukaryotes - 235 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      469867..473717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111099.5NP_186881.2  N2,N2-dimethylguanosine tRNA methyltransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186881.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q682B9, Q9SRU7
      UniProtKB/TrEMBL
      A0A178VEZ9, A0A5S9X8Q3
      Conserved Domains (1) summary
      cl17173
      Location:10466
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...