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    AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821911, updated on 18-Sep-2024

    Summary

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    Official Full Name
    AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein
    Primary source
    TAIR:AT3G23310
    Locus tag
    AT3G23310
    See related
    Araport:AT3G23310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    14
    Sequence:
    Chromosome: 3; NC_003074.8 (8338871..8343737)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640) Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene Splicing factor 3B subunit 5/RDS3 complex subunit 10 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NDR/LATS-family protein kinase genes are indispensable for embryogenesis in Arabidopsis. Yoon HS, et al. FEBS Open Bio, 2021 Sep. PMID 34320276, Free PMC Article
    2. An IRE-like AGC kinase gene, MtIRE, has unique expression in the invasion zone of developing root nodules in Medicago truncatula. Pislariu CI, et al. Plant Physiol, 2007 Jun. PMID 17237187, Free PMC Article
    3. Growth signalling pathways in Arabidopsis and the AGC protein kinases. Bögre L, et al. Trends Plant Sci, 2003 Sep. PMID 13678909
    4. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article
    5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113233.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein
    NP_188973.2
    • AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein; FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cytosol, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase, C-terminal (InterPro:IPR017892), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), AGC-kinase, C-terminal (InterPro:IPR000961), Protein kinase, catalytic domain (InterPro:IPR000719); BEST Arabidopsis thaliana protein match is: AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein (TAIR:AT4G14350.3); Has 108657 Blast hits to 107305 proteins in 3549 species: Archae - 122; Bacteria - 13080; Metazoa - 38792; Fungi - 11766; Plants - 25754; Viruses - 427; Other Eukaryotes - 18716 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8338871..8343737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113233.5 → NP_188973.2  AGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188973.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V5E2, A0A384LNK0, O23314, Q9LW66
      Conserved Domains (1) summary
      cd05599
      Location:118 → 485
      STKc_NDR_like; Catalytic domain of Nuclear Dbf2-Related kinase-like Protein Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version

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