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    integral membrane metal-binding family protein (DUF2296) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829235, updated on 18-Sep-2024

    Summary

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    Official Full Name
    integral membrane metal-binding family protein (DUF2296)
    Primary source
    TAIR:AT4G31080
    Locus tag
    AT4G31080
    See related
    Araport:AT4G31080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6I18.10; F6I18_10
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (15120824..15123527)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene PPR superfamily protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Arg Neighboring gene wall-associated kinase Neighboring gene Wall-associated kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endoplasmic Reticulum (ER) Membrane Proteins (LUNAPARKs) are Required for Proper Configuration of the Cortical ER Network in Plant Cells. Ueda H, et al. Plant Cell Physiol, 2018 Oct 1. PMID 30010972
    2. Arabidopsis Lunapark proteins are involved in ER cisternae formation. Kriechbaumer V, et al. New Phytol, 2018 Aug. PMID 29797722, Free PMC Article
    3. LUNAPARK Is an E3 Ligase That Mediates Degradation of ROOT HAIR DEFECTIVE3 to Maintain a Tubular ER Network in Arabidopsis. Sun J, et al. Plant Cell, 2020 Sep. PMID 32616662, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LUNAPARK Is an E3 Ligase That Mediates Degradation of ROOT HAIR DEFECTIVE3 to Maintain a Tubular ER Network in Arabidopsis.
      Title: LUNAPARK Is an E3 Ligase That Mediates Degradation of ROOT HAIR DEFECTIVE3 to Maintain a Tubular ER Network in Arabidopsis.
    2. AtLNP1 and AtLNP2 are involved in determining the network morphology of the plant endoplasmic reticulum (ER), possibly by regulating the formation of ER cisternae.[AtLNP2]
      Title: Arabidopsis Lunapark proteins are involved in ER cisternae formation.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001203948.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within endoplasmic reticulum cisternal network assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in endoplasmic reticulum tubular network organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    integral membrane metal-binding family protein (DUF2296)
    NP_001190877.1
    • Protein of unknown function (DUF2296); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF2296 (InterPro:IPR019273); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF2296) (TAIR:AT2G24330.1).
    NP_194837.2
    • Protein of unknown function (DUF2296); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF2296 (InterPro:IPR019273); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF2296) (TAIR:AT2G24330.1); Has 339 Blast hits to 333 proteins in 132 species: Archae - 0; Bacteria - 0; Metazoa - 140; Fungi - 115; Plants - 80; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15120824..15123527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119258.4 → NP_194837.2  integral membrane metal-binding family protein (DUF2296) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194837.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2W4, Q3E9T7, Q67YL9, Q8L766
      Conserved Domains (1) summary
      pfam10058
      Location:297 → 347
      zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein

    2. NM_001203948.1 → NP_001190877.1  integral membrane metal-binding family protein (DUF2296) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190877.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FUG5, F4JR68
      Conserved Domains (1) summary
      pfam10058
      Location:331 → 381
      zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein
    Nucleotide Protein
    Heading Accession and Version

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