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    AKN2 APS-kinase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830153, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AKN2
    Official Full Name
    APS-kinase 2
    Primary source
    TAIR:AT4G39940
    Locus tag
    AT4G39940
    See related
    Araport:AT4G39940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ADENOSINE-5'-PHOSPHOSULFATE (APS) KINASE 2; ADENOSINE-5'-PHOSPHOSULFATE-KINASE; APK2; APS-kinase 2; T5J17.110; T5J17_110
    Summary
    adenosine-5'-phosphosulfate-kinase (akn2) mRNA, complete
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    Genomic context

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    See AKN2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (18519599..18521605)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene AT hook motif DNA-binding family protein Neighboring gene uncharacterized protein Neighboring gene cytochrome P450, family 79, subfamily B, polypeptide 2 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular and catalytic properties of Arabidopsis thaliana adenylyl sulfate (APS)-kinase. Lillig CH, et al. Arch Biochem Biophys, 2001 Aug 15. PMID 11488606
    2. Adenosine-5'-phosphosulfate kinase is essential for Arabidopsis viability. Mugford SG, et al. FEBS Lett, 2010 Jan 4. PMID 19903478
    3. Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites. Mugford SG, et al. Plant Cell, 2009 Mar. PMID 19304933, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120157.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables adenylylsulfate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables adenylylsulfate kinase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hydrogen sulfide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within male gamete generation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of glucosinolate biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sulfate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sulfate assimilation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    APS-kinase 2
    NP_195704.1
    • APS-kinase 2 (AKN2); CONTAINS InterPro DOMAIN/s: Adenylylsulphate kinase, C-terminal (InterPro:IPR002891); BEST Arabidopsis thaliana protein match is: APS kinase (TAIR:AT2G14750.1); Has 4962 Blast hits to 4962 proteins in 1492 species: Archae - 54; Bacteria - 3008; Metazoa - 246; Fungi - 282; Plants - 130; Viruses - 0; Other Eukaryotes - 1242 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      18519599..18521605
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120157.4 → NP_195704.1  APS-kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195704.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49196
      UniProtKB/TrEMBL
      A0A178V573, A0A5S9Y0I9
      Conserved Domains (1) summary
      COG0529
      Location:93 → 293
      CysC; Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49196.1

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