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    LPPgamma Phosphatidic acid phosphatase (PAP2) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831801, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LPPgamma
    Official Full Name
    Phosphatidic acid phosphatase (PAP2) family protein
    Primary source
    TAIR:AT5G03080
    Locus tag
    AT5G03080
    See related
    Araport:AT5G03080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15A17.110; F15A17_110; lipid phosphate phosphatase gamma
    Summary
    Encodes a phosphatidic acid phosphatase that can be detected in chloroplast membrane fractions. This gene, LPPgamma appears to be more important for diacylglycerol formation than LPPepsilon1 and LPPepsilon2 in the plastids. Heterozygous lppgamma mutants produce pollen that have defects in pollen tube germination and no homozygous mutants have been recovered.
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    Genomic context

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    See LPPgamma in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (721778..723400)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene striatin-like protein Neighboring gene importin alpha isoform 9 Neighboring gene Mto 1 responding down protein Neighboring gene F-box/RNI-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chloroplast phosphatases LPPγ and LPPε1 facilitate conversion of extraplastidic phospholipids to galactolipids. Cook R, et al. Plant Physiol, 2024 May 31. PMID 38401529
    2. Plastidic phosphatidic acid phosphatases identified in a distinct subfamily of lipid phosphate phosphatases with prokaryotic origin. Nakamura Y, et al. J Biol Chem, 2007 Sep 28. PMID 17652095
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Chloroplast phosphatases LPPgamma and LPPepsilon1 facilitate conversion of extraplastidic phospholipids to galactolipids.
      Title: Chloroplast phosphatases LPPγ and LPPε1 facilitate conversion of extraplastidic phospholipids to galactolipids.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_120386.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within diacylglycerol biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Phosphatidic acid phosphatase (PAP2) family protein
    NP_195928.1
    • Phosphatidic acid phosphatase (PAP2) family protein; FUNCTIONS IN: catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); Has 881 Blast hits to 875 proteins in 378 species: Archae - 15; Bacteria - 412; Metazoa - 127; Fungi - 150; Plants - 85; Viruses - 0; Other Eukaryotes - 92 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      721778..723400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120386.4 → NP_195928.1  Phosphatidic acid phosphatase (PAP2) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195928.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NLA5, Q9LYX7
      UniProtKB/TrEMBL
      A0A178URC2, A0A5S9Y0W6
      Conserved Domains (1) summary
      cd03382
      Location:11 → 171
      PAP2_dolichyldiphosphatase; PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NLA5.1

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