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    AtSPO22 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834894, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AtSPO22
    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT5G48390
    Locus tag
    AT5G48390
    See related
    Araport:AT5G48390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    A. thaliana homologue of yeast SPO22; ATZIP4; MJE7.2; MJE7_2
    Summary
    Defective in meiotic chromosome segregation. It is involved in crossover formation and involved in both male and female meiosis.
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    Genomic context

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    See AtSPO22 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (19612020..19615383)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene BAK1-interacting receptor-like kinase 1 Neighboring gene FRIGIDA-like protein Neighboring gene Glutamate receptor family protein Neighboring gene glutamate receptor 1.3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Zip4/Spo22 is required for class I CO formation but not for synapsis completion in Arabidopsis thaliana. Chelysheva L, et al. PLoS Genet, 2007 May 25. PMID 17530928, Free PMC Article
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within female meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within male meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of synaptonemal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within resolution of meiotic recombination intermediates IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_199650.3
    • ATZIP4; FUNCTIONS IN: binding; INVOLVED IN: female meiosis, resolution of meiotic recombination intermediates, male meiosis; LOCATED IN: chloroplast; CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990), Meiosis specific protein SPO22 (InterPro:IPR013940), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19612020..19615383
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124214.7 → NP_199650.3  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199650.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A5Y6I6, B0M1H3
      UniProtKB/TrEMBL
      A0A654G937
      Conserved Domains (3) summary
      sd00006
      Location:476 → 513
      TPR; TPR repeat [structural motif]
      pfam08631
      Location:191 → 470
      SPO22; Meiosis protein SPO22/ZIP4 like
      pfam12895
      Location:458 → 537
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B0M1H3.1

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