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    SWEET17 Nodulin MtN3 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827274, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SWEET17
    Official Full Name
    Nodulin MtN3 family protein
    Primary source
    TAIR:AT4G15920
    Locus tag
    AT4G15920
    See related
    Araport:AT4G15920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSWEET17; DL4000C; FCAALL.237
    Summary
    Encodes a vacuolar fructose transporter expressed in parenchyma and xylem that controls leaf fructose content. When its expression is reduced, fructose accumulates in leaves.
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    Genomic context

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    See SWEET17 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (9030486..9033648, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pleiotropic regulatory locus 1 Neighboring gene drought-induced 21 Neighboring gene Dynein light chain type 1 family protein Neighboring gene Fumarylacetoacetate (FAA) hydrolase family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Carbohydrate distribution via SWEET17 is critical for Arabidopsis inflorescence branching under drought. Valifard M, et al. J Exp Bot, 2024 Jul 10. PMID 38530289
    2. Vacuolar fructose transporter SWEET17 is critical for root development and drought tolerance. Valifard M, et al. Plant Physiol, 2021 Dec 4. PMID 34597404, Free PMC Article
    3. Leaf fructose content is controlled by the vacuolar transporter SWEET17 in Arabidopsis. Chardon F, et al. Curr Biol, 2013 Apr 22. PMID 23583552
    4. SWEET17, a facilitative transporter, mediates fructose transport across the tonoplast of Arabidopsis roots and leaves. Guo WJ, et al. Plant Physiol, 2014 Feb. PMID 24381066, Free PMC Article
    5. Functional role of oligomerization for bacterial and plant SWEET sugar transporter family. Xuan YH, et al. Proc Natl Acad Sci U S A, 2013 Sep 24. PMID 24027245, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Carbohydrate distribution via SWEET17 is critical for Arabidopsis inflorescence branching under drought.
      Title: Carbohydrate distribution via SWEET17 is critical for Arabidopsis inflorescence branching under drought.
    2. Vacuolar fructose transporter SWEET17 is critical for root development and drought tolerance.
      Title: Vacuolar fructose transporter SWEET17 is critical for root development and drought tolerance.
    3. SWEET17 plays a key role in facilitating bidirectional fructose (Fru) transport across the tonoplast of roots in response to metabolic demand to maintain cytosolic Fru homeostasis.
      Title: SWEET17, a facilitative transporter, mediates fructose transport across the tonoplast of Arabidopsis roots and leaves.
    4. The carrier protein SWEET17 is a major factor controlling fructose content in Arabidopsis leaves. When SWEET17 expression is reduced, either by induced or natural variation, fructose accumulates in leaves, suggesting an enhanced storage capacity.
      Title: Leaf fructose content is controlled by the vacuolar transporter SWEET17 in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_117684.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fructose uniporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbohydrate export IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within fructose export from vacuole to cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Nodulin MtN3 family protein
    NP_193327.5
    • Nodulin MtN3 family protein; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: MtN3/saliva-related transmembrane protein, conserved region (InterPro:IPR018169), RAG1-activating protein 1 homologue (InterPro:IPR018179), RAG1-activating protein-1-related (InterPro:IPR004316); BEST Arabidopsis thaliana protein match is: Nodulin MtN3 family protein (TAIR:AT3G16690.1); Has 980 Blast hits to 942 proteins in 113 species: Archae - 0; Bacteria - 0; Metazoa - 205; Fungi - 0; Plants - 645; Viruses - 0; Other Eukaryotes - 130 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9030486..9033648 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117684.6 → NP_193327.5  Nodulin MtN3 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193327.5

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JKX8, O23441, Q84WN3
      Conserved Domains (1) summary
      pfam03083
      Location:6 → 92
      MtN3_slv; Sugar efflux transporter for intercellular exchange
    Nucleotide Protein
    Heading Accession and Version

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