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    EME1B essential meiotic endonuclease 1B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816748, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EME1B
    Official Full Name
    essential meiotic endonuclease 1B
    Primary source
    TAIR:AT2G22140
    Locus tag
    AT2G22140
    See related
    Araport:AT2G22140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATEME1B; essential meiotic endonuclease 1B; T26C19.20; T26C19_20
    Summary
    Forms a complex with MUS81 that functions as endonuclease in DNA recombination and repair processes.
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    Genomic context

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    See EME1B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (9414557..9418711, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene low-molecular-weight cysteine-rich 35 Neighboring gene uncharacterized protein Neighboring gene binding protein Neighboring gene ECA1 gametogenesis related family protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two distinct MUS81-EME1 complexes from Arabidopsis process Holliday junctions. Geuting V, et al. Plant Physiol, 2009 Jun. PMID 19339504, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001335783.1
    NM_127782.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA recombination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Holliday junction resolvase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    essential meiotic endonuclease 1B
    NP_179804.5
    • essential meiotic endonuclease 1B (EME1B); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166); BEST Arabidopsis thaliana protein match is: essential meiotic endonuclease 1A (TAIR:AT2G21800.1); Has 542 Blast hits to 486 proteins in 142 species: Archae - 0; Bacteria - 42; Metazoa - 170; Fungi - 104; Plants - 48; Viruses - 0; Other Eukaryotes - 178 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9414557..9418711 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127782.6 → NP_179804.5  essential meiotic endonuclease 1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179804.5

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C5H8J1, Q9SIF0
      UniProtKB/TrEMBL
      A0A5S9X0C4, A0A654EW75
      Conserved Domains (1) summary
      cd20083
      Location:253 → 422
      XPF_nuclease_EME; XPF-like nuclease domain of crossover junction endonucleases, EME1, EME2 and similar proteins

    2. NM_001335783.1 → NP_001325038.1  essential meiotic endonuclease 1B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B1X7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    C5H8J1.1

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