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    ARG1 Chaperone DnaJ-domain superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843166, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ARG1
    Official Full Name
    Chaperone DnaJ-domain superfamily protein
    Primary source
    TAIR:AT1G68370
    Locus tag
    AT1G68370
    See related
    Araport:AT1G68370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALTERED RESPONSE TO GRAVITY 1; T22E19.25; T22E19_25
    Summary
    DnaJ-like protein with homology to coiled coils found in cytoskeleton-interacting proteins.
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    Genomic context

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    See ARG1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (25631689..25634780, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene C2H2 and C2HC zinc fingers superfamily protein Neighboring gene Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ARG1 Functions in the Physiological Adaptation of Undifferentiated Plant Cells to Spaceflight. Zupanska AK, et al. Astrobiology, 2017 Nov. PMID 29088549, Free PMC Article
    2. GSA-1/ARG1 protects root gravitropism in Arabidopsis under ammonium stress. Zou N, et al. New Phytol, 2013 Oct. PMID 23782229
    3. ARG1 (altered response to gravity) encodes a DnaJ-like protein that potentially interacts with the cytoskeleton. Sedbrook JC, et al. Proc Natl Acad Sci U S A, 1999 Feb 2. PMID 9927707, Free PMC Article
    4. ARL2, ARG1 and PIN3 define a gravity signal transduction pathway in root statocytes. Harrison BR, et al. Plant J, 2008 Jan. PMID 18047472
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Most of the genes altered in expression in spaceflight in WT cells were found to be Arg1-dependent, suggesting a major role for that gene in the physiological adaptation of undifferentiated cells to spaceflight.
      Title: ARG1 Functions in the Physiological Adaptation of Undifferentiated Plant Cells to Spaceflight.
    2. Under NH4(+) stress, Arabidopsis mutant gsa-1 (gravitropism sensitive to ammonium-1) displayed increased loss of root gravitropism. And, disruption of GSA-1/ARG1 can reduce basipetal auxin transport and the expression of AUX1 protein in root apices. [ARG1] [ALTERED RESPONSE TO GRAVITY1]
      Title: GSA-1/ARG1 protects root gravitropism in Arabidopsis under ammonium stress.
    3. Together these data suggest that ARL2 and ARG1 functionally link gravity sensation in the statocytes to auxin redistribution through the root cap.
      Title: ARL2, ARG1 and PIN3 define a gravity signal transduction pathway in root statocytes.
    Submit: New GeneRIF Correction

    General gene information

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    NM_105508.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cytoskeletal protein binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    NOT involved_in phototropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Chaperone DnaJ-domain superfamily protein
    NP_177004.1
    • ALTERED RESPONSE TO GRAVITY 1 (ARG1); CONTAINS InterPro DOMAIN/s: Molecular chaperone, heat shock protein, Hsp40, DnaJ (InterPro:IPR015609), Heat shock protein DnaJ, N-terminal (InterPro:IPR001623), Heat shock protein DnaJ (InterPro:IPR003095), Heat shock protein DnaJ, conserved site (InterPro:IPR018253); BEST Arabidopsis thaliana protein match is: ARG1-like 1 (TAIR:AT1G24120.1); Has 24672 Blast hits to 24665 proteins in 3308 species: Archae - 176; Bacteria - 9653; Metazoa - 4287; Fungi - 2463; Plants - 2622; Viruses - 27; Other Eukaryotes - 5444 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25631689..25634780 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105508.4 → NP_177004.1  Chaperone DnaJ-domain superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177004.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZSY2
      UniProtKB/TrEMBL
      A0A178WD85, A0A5S9WSQ2, Q0WPQ4, Q1H5A8
      Conserved Domains (3) summary
      COG0484
      Location:16 → 91
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:17 → 79
      DnaJ; DnaJ domain
      cl03075
      Location:288 → 334
      GrpE; nucleotide exchange factor GrpE
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZSY2.1

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