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    NIH nuclear DEIH-boxhelicase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837177, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NIH
    Official Full Name
    nuclear DEIH-boxhelicase
    Primary source
    TAIR:AT1G06670
    Locus tag
    AT1G06670
    See related
    Araport:AT1G06670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DEIH-BOX RNA/DNA HELICASE; F12K11.4; F12K11_4; nuclear DEIH-boxhelicase
    Summary
    nuclear DEIH-box helicase (NIH) encoding a putative RNA and/or DNA helicase homologous to a group of nucleic acid helicases from the DEAD/H family with nuclear DEIH-box helicase (NIH) distinct N- and C-terminal regions that differ from animal DEIH proteins
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    Genomic context

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    See NIH in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (2040410..2047655)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene ncRNA Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit Neighboring gene photosystem II subunit P-1 Neighboring gene NAD(P)-linked oxidoreductase superfamily protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Arabidopsis cDNA encoding a DNA-binding protein that is highly similar to the DEAH family of RNA/DNA helicase genes. Isono K, et al. Nucleic Acids Res, 1999 Sep 15. PMID 10471743, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001331643.1
    NM_100544.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    nuclear DEIH-boxhelicase
    NP_172152.1
    • nuclear DEIH-boxhelicase (NIH); CONTAINS InterPro DOMAIN/s: Helicase-associated domain (InterPro:IPR007502), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), Ankyrin repeat-containing domain (InterPro:IPR020683), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Single-stranded nucleic acid binding R3H (InterPro:IPR001374), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: helicase in vascular tissue and tapetum (TAIR:AT2G30800.1); Has 26020 Blast hits to 16191 proteins in 1841 species: Archae - 22; Bacteria - 7563; Metazoa - 5966; Fungi - 2932; Plants - 1417; Viruses - 339; Other Eukaryotes - 7781 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2040410..2047655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100544.3 → NP_172152.1  nuclear DEIH-boxhelicase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172152.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IDQ6, Q9SHK6, Q9SMG9
      UniProtKB/TrEMBL
      A0A654ECH7
      Conserved Domains (5) summary
      cd06007
      Location:18 → 76
      R3H_DEXH_helicase; R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine ...
      COG1643
      Location:209 → 898
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      sd00045
      Location:475 → 505
      ANK; ANK repeat [structural motif]
      pfam07717
      Location:919 → 1007
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      pfam13857
      Location:475 → 515
      Ank_5; Ankyrin repeats (many copies)

    2. NM_001331643.1 → NP_001321998.1  nuclear DEIH-boxhelicase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASP8, A0A654ECH7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4IDQ6.1

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