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    MCC1 MEIOTIC CONTROL OF CROSSOVERS1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821166, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MCC1
    Official Full Name
    MEIOTIC CONTROL OF CROSSOVERS1
    Primary source
    TAIR:AT3G02980
    Locus tag
    AT3G02980
    See related
    Araport:AT3G02980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13E7.7; F13E7_7; MEIOTIC CONTROL OF CROSSOVERS1
    Summary
    Encodes MEIOTIC CONTROL OF CROSSOVERS1 (MCC1), a GCN5-related histone N-acetyltransferase. MCC1 appeared to be required in meiosis for normal chiasma number and distribution and for chromosome segregation. Activation tagging line has increased level of histone H3 acetylation.
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    Genomic context

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    See MCC1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (670657..672504, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene uncharacterized protein Neighboring gene EXORDIUM like 6 Neighboring gene ncRNA Neighboring gene heat shock transcription factor A1E Neighboring gene EF hand calcium-binding protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Histone hyperacetylation affects meiotic recombination and chromosome segregation in Arabidopsis. Perrella G, et al. Plant J, 2010 Jun 1. PMID 20230492
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide alpha-N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within meiotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    MEIOTIC CONTROL OF CROSSOVERS1
    NP_186948.1
    • MEIOTIC CONTROL OF CROSSOVERS1 (MCC1); FUNCTIONS IN: N-acetyltransferase activity; INVOLVED IN: meiosis, histone H3 acetylation, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Acyl-CoA N-acyltransferase (InterPro:IPR016181); BEST Arabidopsis thaliana protein match is: Acyl-CoA N-acyltransferases (NAT) superfamily protein (TAIR:AT5G16800.2); Has 652 Blast hits to 648 proteins in 194 species: Archae - 48; Bacteria - 59; Metazoa - 253; Fungi - 42; Plants - 110; Viruses - 0; Other Eukaryotes - 140 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      670657..672504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111168.2 → NP_186948.1  MEIOTIC CONTROL OF CROSSOVERS1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186948.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M8T9
      UniProtKB/TrEMBL
      A0A178VBT3, A0A5S9X9P5
      Conserved Domains (1) summary
      COG0456
      Location:27 → 199
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

    2. NM_001337453.1 → NP_001326201.1  MEIOTIC CONTROL OF CROSSOVERS1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LNJ6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M8T9.1

    Gene LinkOut

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