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    Granulin repeat cysteine protease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821473, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Granulin repeat cysteine protease family protein
    Primary source
    TAIR:AT3G19390
    Locus tag
    AT3G19390
    See related
    Araport:AT3G19390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (6722825..6725110)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene filament-like protein (DUF869) Neighboring gene plant U-box 25 Neighboring gene Cysteine proteinases superfamily protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Kunitz-type protease inhibitor regulates programmed cell death during flower development in Arabidopsis thaliana. Boex-Fontvieille E, et al. J Exp Bot, 2015 Oct. PMID 26160583
    2. Arabidopsis protein disulfide isomerase-5 inhibits cysteine proteases during trafficking to vacuoles before programmed cell death of the endothelium in developing seeds. Andème Ondzighi C, et al. Plant Cell, 2008 Aug. PMID 18676877, Free PMC Article
    3. PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis. Nishimura N, et al. Plant J, 2010 Jan. PMID 19874541, Free PMC Article
    4. Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry. Huang H, et al. Mol Cell Proteomics, 2016 Jan. PMID 26545401, Free PMC Article
    5. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112826.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Granulin repeat cysteine protease family protein
    NP_566633.1
    • Granulin repeat cysteine protease family protein; FUNCTIONS IN: cysteine-type endopeptidase activity, cysteine-type peptidase activity; INVOLVED IN: proteolysis; LOCATED IN: endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase C1A, papain (InterPro:IPR013128), Proteinase inhibitor I29, cathepsin propeptide (InterPro:IPR013201), Granulin (InterPro:IPR000118), Peptidase C1A, papain C-terminal (InterPro:IPR000668), Peptidase, cysteine peptidase active site (InterPro:IPR000169); BEST Arabidopsis thaliana protein match is: Granulin repeat cysteine protease family protein (TAIR:AT5G43060.1); Has 9061 Blast hits to 8168 proteins in 770 species: Archae - 67; Bacteria - 297; Metazoa - 4335; Fungi - 6; Plants - 1937; Viruses - 140; Other Eukaryotes - 2279 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6722825..6725110
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112826.4 → NP_566633.1  Granulin repeat cysteine protease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566633.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LT78
      UniProtKB/TrEMBL
      A0A178VHV4, A0A5S9XDS3
      Conserved Domains (3) summary
      smart00277
      Location:364 → 420
      GRAN; Granulin
      smart00848
      Location:43 → 99
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:129 → 345
      Peptidase_C1; Papain family cysteine protease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LT78.1

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