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    ROPGEF11 rop guanine nucleotide exchange factor-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841654, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROPGEF11
    Official Full Name
    rop guanine nucleotide exchange factor-like protein
    Primary source
    TAIR:AT1G52240
    Locus tag
    AT1G52240
    See related
    Araport:AT1G52240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATROPGEF11; F9I5.12; F9I5_12; phytochrome interacting RopGEF 1; PIRF1; RHO guanyl-nucleotide exchange factor 11; ROP (rho of plants) guanine nucleotide exchange factor 11
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily .
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    Genomic context

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    See ROPGEF11 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (19455495..19458069, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene CURVATURE THYLAKOID protein Neighboring gene photosystem I subunit H2 Neighboring gene dynein light chain LC6, flagellar outer arm-like protein Neighboring gene PDI-like 1-5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Release of GTP Exchange Factor Mediated Down-Regulation of Abscisic Acid Signal Transduction through ABA-Induced Rapid Degradation of RopGEFs. Li Z, et al. PLoS Biol, 2016 May. PMID 27192441, Free PMC Article
    2. A small GTPase activator protein interacts with cytoplasmic phytochromes in regulating root development. Shin DH, et al. J Biol Chem, 2010 Oct 15. PMID 20551316, Free PMC Article
    3. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Gu Y, et al. Plant Cell, 2006 Feb. PMID 16415208, Free PMC Article
    4. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that phytochrome and ROP signaling are interconnected through PIRF1 in regulating the root growth and development in Arabidopsis.
      Title: A small GTPase activator protein interacts with cytoplasmic phytochromes in regulating root development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_104103.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    rop guanine nucleotide exchange factor-like protein
    NP_175634.6
    • RHO guanyl-nucleotide exchange factor 11 (ROPGEF11); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512), Dynein light chain, type 1/2 (InterPro:IPR001372); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 13 (TAIR:AT3G16130.1); Has 1099 Blast hits to 1098 proteins in 168 species: Archae - 0; Bacteria - 0; Metazoa - 490; Fungi - 40; Plants - 487; Viruses - 0; Other Eukaryotes - 82 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19455495..19458069 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104103.6 → NP_175634.6  rop guanine nucleotide exchange factor-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3LF51, F4ICV0, Q9M811
      UniProtKB/TrEMBL
      A0A178W8V0, A0A5S9WP17
      Conserved Domains (1) summary
      pfam03759
      Location:105 → 449
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M811.2

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