U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NDT2 NAD+ transporter 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839124, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NDT2
    Official Full Name
    NAD+ transporter 2
    Primary source
    TAIR:AT1G25380
    Locus tag
    AT1G25380
    See related
    Araport:AT1G25380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA NAD+ TRANSPORTER 2; ATNDT2; F4F7.45; NAD+ transporter 2
    Summary
    Encodes a mitochondrial-localized NAD+ transporter that transports NAD+ in a counter exchange mode with ADP and AMP in vitro.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NDT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (8903405..8906455)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene hypothetical protein (DUF1639) Neighboring gene Metallo-hydrolase/oxidoreductase superfamily protein Neighboring gene Protein kinase superfamily protein Neighboring gene miscRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis. Feitosa-Araujo E, et al. Plant Cell Physiol, 2020 May 1. PMID 32065636, Free PMC Article
    2. Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins. Palmieri F, et al. J Biol Chem, 2009 Nov 6. PMID 19745225, Free PMC Article
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis.
      Title: Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis.
    2. NDT1 resides in chloroplasts, whereas NDT2 locates to mitochondria.
      Title: Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001332677.1
    NM_102349.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within NAD transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within NAD transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    NAD+ transporter 2
    NP_564233.1
    • NAD+ transporter 2 (NDT2); FUNCTIONS IN: binding, NAD transporter activity; INVOLVED IN: transport, NAD transport, mitochondrial transport; LOCATED IN: mitochondrial inner membrane, membrane; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial carrier protein (InterPro:IPR002067), Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: NAD+ transporter 1 (TAIR:AT2G47490.1); Has 30606 Blast hits to 14728 proteins in 470 species: Archae - 0; Bacteria - 8; Metazoa - 12581; Fungi - 9084; Plants - 5612; Viruses - 5; Other Eukaryotes - 3316 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8903405..8906455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102349.4 → NP_564233.1  NAD+ transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564233.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4A3J5, Q8RWA5, Q9C6K8, Q9FRI7
      UniProtKB/TrEMBL
      A0A178WGZ3, A0A5S9VUS6
      Conserved Domains (1) summary
      pfam00153
      Location:213 → 307
      Mito_carr; Mitochondrial carrier protein

    2. NM_001332677.1 → NP_001321077.1  NAD+ transporter 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4A3J5, Q8RWA5, Q9C6K8, Q9FRI7
      UniProtKB/TrEMBL
      A0A178WGZ3, A0A5S9VUS6
      Conserved Domains (1) summary
      pfam00153
      Location:213 → 307
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RWA5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools