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    FBA2 fructose-bisphosphate aldolase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830052, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FBA2
    Official Full Name
    fructose-bisphosphate aldolase 2
    Primary source
    TAIR:AT4G38970
    Locus tag
    AT4G38970
    See related
    Araport:AT4G38970
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtFBA2; F19H22.70; F19H22_70; fructose-bisphosphate aldolase 2
    Summary
    Protein is tyrosine-phosphorylated and its phosphorylation state is modulated in response to ABA in Arabidopsis thaliana seeds.
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    Genomic context

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    See FBA2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (18163496..18166008, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ATP binding microtubule motor family protein Neighboring gene B-box type zinc finger family protein Neighboring gene uncharacterized protein Neighboring gene glycosyl hydrolase 9B16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of plant cytosolic aldolase functions by redox-modifications. van der Linde K, et al. Plant Physiol Biochem, 2011 Sep. PMID 21782461
    2. Protein tyrosine kinases and protein tyrosine phosphatases are involved in abscisic acid-dependent processes in Arabidopsis seeds and suspension cells. Ghelis T, et al. Plant Physiol, 2008 Nov. PMID 18768909, Free PMC Article
    3. Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana. Li Q, et al. PLoS Genet, 2015 May. PMID 25933434, Free PMC Article
    4. Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles. Vidi PA, et al. J Biol Chem, 2006 Apr 21. PMID 16414959
    5. High light response of the thylakoid proteome in arabidopsis wild type and the ascorbate-deficient mutant vtc2-2. A comparative proteomics study. Giacomelli L, et al. Plant Physiol, 2006 Jun. PMID 16648217, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120057.4
    NM_202981.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fructose-bisphosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fructose-bisphosphate aldolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gluconeogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycolytic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within pentose-phosphate shunt TAS
    Traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastoglobule HDA PubMed 
    located_in thylakoid HDA PubMed 

    General protein information

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    Preferred Names
    fructose-bisphosphate aldolase 2
    NP_568049.1
    • fructose-bisphosphate aldolase 2 (FBA2); FUNCTIONS IN: fructose-bisphosphate aldolase activity, catalytic activity; INVOLVED IN: response to cadmium ion, pentose-phosphate shunt, response to abscisic acid stimulus; LOCATED IN: in 7 components; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Fructose-bisphosphate aldolase, class-I (InterPro:IPR000741); BEST Arabidopsis thaliana protein match is: fructose-bisphosphate aldolase 1 (TAIR:AT2G21330.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_974710.1
    • fructose-bisphosphate aldolase 2 (FBA2); FUNCTIONS IN: fructose-bisphosphate aldolase activity, catalytic activity; INVOLVED IN: response to cadmium ion, pentose-phosphate shunt, response to abscisic acid stimulus; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Fructose-bisphosphate aldolase, class-I (InterPro:IPR000741); BEST Arabidopsis thaliana protein match is: fructose-bisphosphate aldolase 1 (TAIR:AT2G21330.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      18163496..18166008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120057.4 → NP_568049.1  fructose-bisphosphate aldolase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568049.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XEU6, Q944G9, Q9SVJ6
      UniProtKB/TrEMBL
      A0A178UW98, A0A5S9Y0T1, A0A7G2F3W8
      Conserved Domains (1) summary
      cl21457
      Location:1 → 398
      TIM; TIM-like beta/alpha barrel domains

    2. NM_202981.1 → NP_974710.1  fructose-bisphosphate aldolase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974710.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JUJ5
      Conserved Domains (1) summary
      cl21457
      Location:2 → 323
      TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q944G9.2

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