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    FTSH6 FTSH protease 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831377, updated on 18-Sep-2024

    Summary

    Official Symbol
    FTSH6
    Official Full Name
    FTSH protease 6
    Primary source
    TAIR:AT5G15250
    Locus tag
    AT5G15250
    See related
    Araport:AT5G15250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATFTSH6; F8M21.140; F8M21_140; FTSH protease 6
    Summary
    Encodes an FtsH protease that is localized to the chloroplast. AtFtsH6 is involved in the degradation of both Lhcb3 and Lhcb1 during senescence and high-light acclimation.
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    Genomic context

    See FTSH6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (4950359..4952803, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene GAST1 protein homolog 4 Neighboring gene Transmembrane amino acid transporter family protein Neighboring gene ribosomal protein L34e superfamily protein Neighboring gene uncharacterized protein

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    FTSH protease 6
    NP_001318565.1
    • FTSH protease 6 (FTSH6); CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41, FtsH extracellular (InterPro:IPR011546), Peptidase M41 (InterPro:IPR000642); BEST Arabidopsis thaliana protein match is: FtsH extracellular protease family (TAIR:AT2G30950.1).
    NP_568311.2
    • FTSH protease 6 (FTSH6); CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: FtsH extracellular protease family (TAIR:AT2G30950.1); Has 36407 Blast hits to 33937 proteins in 3209 species: Archae - 1599; Bacteria - 12070; Metazoa - 5030; Fungi - 3920; Plants - 3423; Viruses - 32; Other Eukaryotes - 10333 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4950359..4952803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343392.1NP_001318565.1  FTSH protease 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K9Q6
    2. NM_121529.2NP_568311.2  FTSH protease 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568311.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1PDW5, Q9LXF7
      UniProtKB/TrEMBL
      A0A5S9Y4V5
      Conserved Domains (4) summary
      CHL00176
      Location:91671
      ftsH; cell division protein; Validated
      pfam00004
      Location:260393
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam01434
      Location:472663
      Peptidase_M41; Peptidase family M41
      pfam06480
      Location:88161
      FtsH_ext; FtsH Extracellular