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    ETFBETA electron transfer flavoprotein beta [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834363, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ETFBETA
    Official Full Name
    electron transfer flavoprotein beta
    Primary source
    TAIR:AT5G43430
    Locus tag
    AT5G43430
    See related
    Araport:AT5G43430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    electron transfer flavoprotein beta; MWF20.14; MWF20_14
    Summary
    Encodes the electron transfer flavoprotein ETF beta, a putative subunit of the mitochondrial electron transfer flavoprotein complex (ETF alpha is At1g50940) in Arabidopsis. Mutations of the ETF beta gene result in accelerated senescence and early death compared to wild-type during extended darkness. Also involved in the catabolism of leucine and chlorophyll degradation pathway activated during darkness-induced carbohydrate deprivation.
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    Genomic context

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    See ETFBETA in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (17453517..17455297)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene RING/U-box superfamily protein Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mitochondrial electron transfer flavoprotein complex is essential for survival of Arabidopsis in extended darkness. Ishizaki K, et al. Plant J, 2006 Sep. PMID 16923016
    2. Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Taylor NL, et al. Plant Physiol, 2004 Feb. PMID 14764908, Free PMC Article
    3. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036925.2
    NM_001085230.2
    NM_123709.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-leucine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chlorophyll catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    electron transfer flavoprotein beta
    NP_001032002.1
    • electron transfer flavoprotein beta (ETFBETA); FUNCTIONS IN: electron carrier activity; INVOLVED IN: chlorophyll catabolic process, leucine catabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Electron transfer flavoprotein, beta subunit (InterPro:IPR012255), Electron transfer flavoprotein, beta-subunit, conserved site (InterPro:IPR000049), Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (InterPro:IPR014730); Has 6473 Blast hits to 6473 proteins in 1645 species: Archae - 150; Bacteria - 3948; Metazoa - 143; Fungi - 135; Plants - 49; Viruses - 0; Other Eukaryotes - 2048 (source: NCBI BLink).
    NP_001078699.1
    • electron transfer flavoprotein beta (ETFBETA); FUNCTIONS IN: electron carrier activity; INVOLVED IN: chlorophyll catabolic process, leucine catabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Electron transfer flavoprotein, beta-subunit, conserved site (InterPro:IPR000049), Electron transfer flavoprotein, beta subunit (InterPro:IPR012255), Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (InterPro:IPR014730); Has 6953 Blast hits to 6953 proteins in 1650 species: Archae - 156; Bacteria - 4220; Metazoa - 148; Fungi - 127; Plants - 47; Viruses - 0; Other Eukaryotes - 2255 (source: NCBI BLink).
    NP_199156.1
    • electron transfer flavoprotein beta (ETFBETA); FUNCTIONS IN: electron carrier activity; INVOLVED IN: chlorophyll catabolic process, leucine catabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (InterPro:IPR014730), Electron transfer flavoprotein, beta-subunit, conserved site (InterPro:IPR000049), Electron transfer flavoprotein, beta subunit (InterPro:IPR012255); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17453517..17455297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344482.1 → NP_001332757.1  electron transfer flavoprotein beta [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UFE9, A0A1R7T3K7

    2. NM_123709.4 → NP_199156.1  electron transfer flavoprotein beta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199156.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MRD3, Q2V317, Q8LFE0, Q9LSW8
      UniProtKB/TrEMBL
      A0A178UFE9
      Conserved Domains (1) summary
      COG2086
      Location:1 → 248
      FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]

    3. NM_001085230.2 → NP_001078699.1  electron transfer flavoprotein beta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078699.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B9DH42
      Conserved Domains (1) summary
      COG2086
      Location:1 → 216
      FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]

    4. NM_001036925.2 → NP_001032002.1  electron transfer flavoprotein beta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032002.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B9DG90
      Conserved Domains (1) summary
      COG2086
      Location:1 → 177
      FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LSW8.1

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