U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PDLP1 plasmodesmata-located protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834421, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PDLP1
    Official Full Name
    plasmodesmata-located protein 1
    Primary source
    TAIR:AT5G43980
    Locus tag
    AT5G43980
    See related
    Araport:AT5G43980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MRH10.9; MRH10_9; PDLP1A; plasmodesmata-located protein 1; PLASMODESMATA-LOCATED PROTEIN 1A
    Summary
    Encodes a plasmodesmal protein that affects the intercellular movement of molecules through the plasmodesmata. The cytoplasmic C-terminal portion of the protein is connected to the apoplastic N-terminal portion of the protein by a single transmembrane domain (TMD). It is transported to the plasmodesmata through the secretory pathway. PDLP1 has two DUF26 domains and a signal peptide, but the proper localization of the protein appears to depend on the TMD.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PDLP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (17694680..17696690, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein Neighboring gene translocase of outer membrane 22-V Neighboring gene SET-domain containing protein lysine methyltransferase family protein Neighboring gene Glutathione S-transferase family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Plasmodesmata Localizing Proteins Regulate Transport and Signaling during Systemic Acquired Immunity in Plants. Lim GH, et al. Cell Host Microbe, 2016 Apr 13. PMID 27078071
    2. Plasmodesmata-located protein overexpression negatively impacts the manifestation of systemic acquired resistance and the long-distance movement of Defective in Induced Resistance1 in Arabidopsis. Carella P, et al. Plant Biol (Stuttg), 2015 Mar. PMID 25296648
    3. A family of plasmodesmal proteins with receptor-like properties for plant viral movement proteins. Amari K, et al. PLoS Pathog, 2010 Sep 23. PMID 20886105, Free PMC Article
    4. Specific targeting of a plasmodesmal protein affecting cell-to-cell communication. Thomas CL, et al. PLoS Biol, 2008 Jan. PMID 18215111, Free PMC Article
    5. The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition. Caillaud MC, et al. PLoS Pathog, 2014 Oct. PMID 25393742, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Plasmodesmata localizing proteins PDLP1 and PDLP5 are required for systemic acquired resistance.
      Title: Plasmodesmata Localizing Proteins Regulate Transport and Signaling during Systemic Acquired Immunity in Plants.
    2. The pdlp1,2,3 triple mutant is more susceptible to Hyaloperonospora arabidopsidis (Hpa) while overexpression of PDLP1 enhances plant resistance, suggesting that PDLPs enhance basal immunity against Hpa.
      Title: The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition.
    3. PDLP1 plays role in systemic acquired resistance and the long-distance movement of DIR1 protein in Arabidopsis.
      Title: Plasmodesmata-located protein overexpression negatively impacts the manifestation of systemic acquired resistance and the long-distance movement of Defective in Induced Resistance1 in Arabidopsis.
    4. PDLP1a is targeted to plasmodesmata via the secretory pathway in a Brefeldin A-sensitive and COPII-dependent manner
      Title: Specific targeting of a plasmodesmal protein affecting cell-to-cell communication.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_123765.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within plasmodesmata-mediated intercellular transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within transport of virus in multicellular host IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in plasmodesma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    plasmodesmata-located protein 1
    NP_199211.2
    • plasmodesmata-located protein 1 (PDLP1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF26 (InterPro:IPR002902); BEST Arabidopsis thaliana protein match is: plasmodesmata-located protein 3 (TAIR:AT2G33330.1); Has 956 Blast hits to 914 proteins in 25 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 956; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17694680..17696690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123765.3 → NP_199211.2  plasmodesmata-located protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199211.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GXV7, Q9FNC8
      UniProtKB/TrEMBL
      A0A5S9YAQ3, A0A654G7S3
      Conserved Domains (1) summary
      pfam01657
      Location:32 → 132
      Stress-antifung; Salt stress response/antifungal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GXV7.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools