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    CB5-E cytochrome B5 isoform E [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835438, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CB5-E
    Official Full Name
    cytochrome B5 isoform E
    Primary source
    TAIR:AT5G53560
    Locus tag
    AT5G53560
    See related
    Araport:AT5G53560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS CYTOCHROME B5 ISOFORM E; ATB5-A; ATCB5-E; B5 #2; cytochrome B5 isoform E
    Summary
    Encodes a cytochrome b5 isoform that can be reduced by AtCBR, a cytochrome b5 reductase.
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    Genomic context

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    See CB5-E in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (21759329..21760578)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene YELLOW STRIPE like 3 Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene NAD(P)-linked oxidoreductase superfamily protein Neighboring gene SAUR-like auxin-responsive protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biochemical Investigation of Membrane-Bound Cytochrome b5 and the Catalytic Domain of Cytochrome b5 Reductase from Arabidopsis thaliana. Iqbal T, et al. Biochemistry, 2022 May 17. PMID 35475372
    2. Microsomal electron transfer in higher plants: cloning and heterologous expression of NADH-cytochrome b5 reductase from Arabidopsis. Fukuchi-Mizutani M, et al. Plant Physiol, 1999 Jan. PMID 9880378, Free PMC Article
    3. Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria. Hwang YT, et al. Plant Cell, 2004 Nov. PMID 15486098, Free PMC Article
    4. Intracellular sorting of the tail-anchored protein cytochrome b5 in plants: a comparative study using different isoforms from rabbit and Arabidopsis. Maggio C, et al. J Exp Bot, 2007. PMID 17322552
    5. Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis ECERIFERUM1 and ECERIFERUM3 are core components of a very-long-chain alkane synthesis complex. Bernard A, et al. Plant Cell, 2012 Jul. PMID 22773744, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Biochemical Investigation of Membrane-Bound Cytochrome b5 and the Catalytic Domain of Cytochrome b5 Reductase from Arabidopsis thaliana.
      Title: Biochemical Investigation of Membrane-Bound Cytochrome b5 and the Catalytic Domain of Cytochrome b5 Reductase from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124736.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast thylakoid membrane HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    cytochrome B5 isoform E
    NP_200168.1
    • cytochrome B5 isoform E (CB5-E); FUNCTIONS IN: heme binding; LOCATED IN: chloroplast thylakoid membrane, endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane, vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome b5, heme-binding site (InterPro:IPR018506), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: cytochrome B5 isoform B (TAIR:AT2G32720.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21759329..21760578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124736.4 → NP_200168.1  cytochrome B5 isoform E [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200168.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42342, Q9SB05
      UniProtKB/TrEMBL
      A0A178USU5, A0A5S9YDN0
      Conserved Domains (1) summary
      pfam00173
      Location:9 → 81
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42342.2

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