PRF3 profilin [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PRF3
Official Full Name: profilin
Primary source: TAIR:AT5G56600
Locus tag: AT5G56600
See related: Araport:AT5G56600
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MIK19.4; MIK19_4; PFN3; PROFILIN; profilin 3; PROFILIN 3
Summary: Encodes profilin3, a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton. Originally known as profilin5, and later named profilin3. Expressed in vegetative organs.
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Genomic context

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See PRF3 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 3

Sequence:: Chromosome: 5; NC_003076.8 (22909882..22910710, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results suggest that the dwarf phenotype of the PRF3 overexpression seedlings may be related to a reduction in cell length and F-actin rearrangement.
Title: Overexpression of profilin 3 affects cell elongation and F-actin organization in Arabidopsis thaliana.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001125974.2

Supported by ESTs:

NM_125043.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin filament polymerization	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within lateral root development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of unidimensional cell growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within seed germination	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within seedling development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plastid	HDA more info	PubMed

General protein information

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Preferred Names: profilin

NP_001119446.2

profilin 3 (PRF3); FUNCTIONS IN: actin binding; INVOLVED IN: cytoskeleton organization, actin cytoskeleton organization; LOCATED IN: nucleus, actin cytoskeleton, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Profilin/allergen (InterPro:IPR002097), Profilin, plant (InterPro:IPR005455); BEST Arabidopsis thaliana protein match is: profilin 1 (TAIR:AT2G19760.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NP_200471.3

profilin 3 (PRF3); FUNCTIONS IN: actin binding; INVOLVED IN: cytoskeleton organization, actin cytoskeleton organization; LOCATED IN: nucleus, actin cytoskeleton, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Profilin/allergen (InterPro:IPR002097), Profilin, plant (InterPro:IPR005455); BEST Arabidopsis thaliana protein match is: profilin 1 (TAIR:AT2G19760.1); Has 942 Blast hits to 941 proteins in 249 species: Archae - 0; Bacteria - 2; Metazoa - 141; Fungi - 125; Plants - 583; Viruses - 0; Other Eukaryotes - 91 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

22909882..22910710 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_125043.4 → NP_200471.3 profilin [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A5S9YGY5, A0A654GC40

Conserved Domains (1) summary

pfam00235
Location:1 → 128

Profilin
NM_001125974.2 → NP_001119446.2 profilin [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FE63