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    HCD1 3-hydroxyacyl-CoA dehydratase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827089, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HCD1
    Official Full Name
    3-hydroxyacyl-CoA dehydratase 1
    Primary source
    TAIR:AT4G14440
    Locus tag
    AT4G14440
    See related
    Araport:AT4G14440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-hydroxyacyl-CoA dehydratase 1; ARABIDOPSIS THALIANA DELTA(3); ATECI3; DELTA(2)-ENOYL COA ISOMERASE 3; DELTA(3); DL3260C; ECI3; FCAALL.212
    Summary
    encodes a cytosolic delta3, delta2-enoyl CoA isomerase, involved in unsaturated fatty acid degradation
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    Genomic context

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    See HCD1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (8306590..8307934, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene HR-like lesion-inducing protein-like protein Neighboring gene indole-3-butyric acid response 10 Neighboring gene uncharacterized protein Neighboring gene Target SNARE coiled-coil domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Peroxisomal Delta(3),Delta(2)-enoyl CoA isomerases and evolution of cytosolic paralogues in embryophytes. Goepfert S, et al. Plant J, 2008 Dec. PMID 18657232
    2. VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. Ceserani T, et al. Plant J, 2009 Mar. PMID 19000166, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_117523.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carnitine racemase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables delta(3)-delta(2)-enoyl-CoA isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables delta(3)-delta(2)-enoyl-CoA isomerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fatty acid catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-hydroxyacyl-CoA dehydratase 1
    NP_193180.1
    • 3-hydroxyacyl-CoA dehydratase 1 (HCD1); CONTAINS InterPro DOMAIN/s: Crotonase, core (InterPro:IPR001753); BEST Arabidopsis thaliana protein match is: indole-3-butyric acid response 10 (TAIR:AT4G14430.1); Has 14429 Blast hits to 14428 proteins in 1575 species: Archae - 280; Bacteria - 10321; Metazoa - 775; Fungi - 259; Plants - 265; Viruses - 0; Other Eukaryotes - 2529 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      8306590..8307934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117523.4 → NP_193180.1  3-hydroxyacyl-CoA dehydratase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193180.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23300
      UniProtKB/TrEMBL
      A0A178UXH2, A0A5S9XSD5
      Conserved Domains (1) summary
      PLN02267
      Location:1 → 236
      PLN02267; enoyl-CoA hydratase/isomerase family protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23300.1

    Gene LinkOut

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