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    GLR5 glutamate receptor 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817801, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLR5
    Official Full Name
    glutamate receptor 5
    Primary source
    TAIR:AT2G32400
    Locus tag
    AT2G32400
    See related
    Araport:AT2G32400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGLR3.7; GLR3.7; GLUTAMATE RECEPTOR 3.7; glutamate receptor 5; T32F6.8; T32F6_8
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    Genomic context

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    See GLR5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (13752263..13756893, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene homeodomain GLABROUS 3 Neighboring gene Transmembrane protein 97, Putative Neighboring gene glutamate receptor 3.5 Neighboring gene AXR1-like protein Neighboring gene Polynucleotidyl transferase, ribonuclease H fold protein with HRDC domain-containing protein Neighboring gene Galactosyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis glutamate receptor GLR3.7 is involved in abscisic acid response. Chen PY, et al. Plant Signal Behav, 2021 Dec 2. PMID 34763610, Free PMC Article
    2. Glutamate receptor-like genes form Ca2+ channels in pollen tubes and are regulated by pistil D-serine. Michard E, et al. Science, 2011 Apr 22. PMID 21415319
    3. Inter-subunit interactions between glutamate-like receptors in Arabidopsis. Price MB, et al. Plant Signal Behav, 2013. PMID 24300102, Free PMC Article
    4. The identity of plant glutamate receptors. Lacombe B, et al. Science, 2001 May 25. PMID 11379626
    5. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128799.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glutamate receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables intracellularly ligand-gated monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in calcium-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cellular response to amino acid stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within intracellular calcium ion homeostasis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    glutamate receptor 5
    NP_565744.1
    • glutamate receptor 5 (GLR5); FUNCTIONS IN: protein binding, intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Extracellular ligand-binding receptor (InterPro:IPR001828), GPCR, family 3, gamma-aminobutyric acid receptor, type B (InterPro:IPR002455), Glutamate receptor-related (InterPro:IPR015683), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 3.4 (TAIR:AT1G05200.2); Has 6965 Blast hits to 6802 proteins in 627 species: Archae - 64; Bacteria - 977; Metazoa - 4763; Fungi - 0; Plants - 634; Viruses - 0; Other Eukaryotes - 527 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13752263..13756893 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128799.4 → NP_565744.1  glutamate receptor 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565744.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SDQ4, Q9ZV68
      UniProtKB/TrEMBL
      A0A5S9X386
      Conserved Domains (4) summary
      cd06366
      Location:32 → 416
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      cd13686
      Location:458 → 800
      GluR_Plant; Plant glutamate receptor domain; the type 2 periplasmic binding protein fold
      pfam00060
      Location:581 → 832
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:46 → 396
      ANF_receptor; Receptor family ligand binding region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SDQ4.2

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