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    Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843196, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein
    Primary source
    TAIR:AT1G68660
    Locus tag
    AT1G68660
    See related
    Araport:AT1G68660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24J5.10; F24J5_10
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (25777851..25779249, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene PLAC8 family protein Neighboring gene bZIP transcription factor family protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein family (UPF0016) Neighboring gene myb-like transcription factor family protein Neighboring gene SH3/FCH domain protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural features of the plant N-recognin ClpS1 and sequence determinants in its targets that govern substrate selection. Aguilar Lucero D, et al. FEBS Lett, 2021 Jun. PMID 33792910
    2. A Gatekeeper Residue of ClpS1 from Arabidopsis thaliana Chloroplasts Determines its Affinity Towards Substrates of the Bacterial N-End Rule. Colombo CV, et al. Plant Cell Physiol, 2018 Mar 1. PMID 29401302
    3. Discovery of a Unique Clp Component, ClpF, in Chloroplasts: A Proposed Binary ClpF-ClpS1 Adaptor Complex Functions in Substrate Recognition and Delivery. Nishimura K, et al. Plant Cell, 2015 Oct. PMID 26419670, Free PMC Article
    4. ClpS1 is a conserved substrate selector for the chloroplast Clp protease system in Arabidopsis. Nishimura K, et al. Plant Cell, 2013 Jun. PMID 23898032, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structural features of the plant N-recognin ClpS1 and sequence determinants in its targets that govern substrate selection.
      Title: Structural features of the plant N-recognin ClpS1 and sequence determinants in its targets that govern substrate selection.
    2. A ClpS1-interacting protein in Arabidopsis thaliana, ClpF, can interact with the Clp substrate glutamyl-tRNA reductase. ClpF and ClpS1 mutually stimulate their association with ClpC.
      Title: Discovery of a Unique Clp Component, ClpF, in Chloroplasts: A Proposed Binary ClpF-ClpS1 Adaptor Complex Functions in Substrate Recognition and Delivery.
    3. Data show that ClpS1 (AT1G68660) interacts with plastid ClpC1 (AT5G50920), ClpC2 (AT3G48870), but not with ClpT1 (AT4G25370) or ClpT2 (AT4G12060).
      Title: ClpS1 is a conserved substrate selector for the chloroplast Clp protease system in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001084325.1
    NM_105538.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-macromolecule adaptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of proteolysis involved in protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein
    NP_001077794.1
    • Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: protein catabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Adaptor protein ClpS, core (InterPro:IPR003769), Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like (InterPro:IPR014719); Has 122 Blast hits to 122 proteins in 49 species: Archae - 0; Bacteria - 62; Metazoa - 0; Fungi - 0; Plants - 57; Viruses - 0; Other Eukaryotes - 3 (source: NCBI BLink).
    NP_564937.1
    • Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: protein catabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Adaptor protein ClpS, core (InterPro:IPR003769), Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like (InterPro:IPR014719); Has 638 Blast hits to 638 proteins in 172 species: Archae - 0; Bacteria - 350; Metazoa - 0; Fungi - 0; Plants - 71; Viruses - 0; Other Eukaryotes - 217 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25777851..25779249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105538.3 → NP_564937.1  Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564937.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MS26, Q9SX29
      UniProtKB/TrEMBL
      A0A178WMY2, A0A5S9WQT6
      Conserved Domains (1) summary
      cl00933
      Location:77 → 155
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    2. NM_001084325.1 → NP_001077794.1  Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077794.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E521
      Conserved Domains (1) summary
      cl00933
      Location:77 → 125
      ClpS; ATP-dependent Clp protease adaptor protein ClpS
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SX29.1

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