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    MGT2 magnesium transporter 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838171, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MGT2
    Official Full Name
    magnesium transporter 2
    Primary source
    TAIR:AT1G16010
    Locus tag
    AT1G16010
    See related
    Araport:AT1G16010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtMGT2; AtMRS2-1; magnesium transporter 2; MRS2-1; T24D18.11; T24D18_11
    Summary
    Transmembrane magnesium transporter. One of nine family members.
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    Genomic context

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    See MGT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (5495373..5497723, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NDH-dependent cyclic electron flow 1 Neighboring gene cyclic nucleotide gated channel 7 Neighboring gene GAG1At protein Neighboring gene vacuolar fusion protein (DUF1712) Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Membrane protein interactions between different Arabidopsis thaliana MRS2-type magnesium transporters are highly permissive. Schmitz J, et al. Biochim Biophys Acta, 2013 Sep. PMID 23732234
    2. Magnesium transporters, MGT2/MRS2-1 and MGT3/MRS2-5, are important for magnesium partitioning within Arabidopsis thaliana mesophyll vacuoles. Conn SJ, et al. New Phytol, 2011 May. PMID 21261624
    3. Magnesium deficiency phenotypes upon multiple knockout of Arabidopsis thaliana MRS2 clade B genes can be ameliorated by concomitantly reduced calcium supply. Lenz H, et al. Plant Cell Physiol, 2013 Jul. PMID 23628997
    4. A root-expressed magnesium transporter of the MRS2/MGT gene family in Arabidopsis thaliana allows for growth in low-Mg2+ environments. Gebert M, et al. Plant Cell, 2009 Dec. PMID 19966073, Free PMC Article
    5. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate obtaining homozygous AtMRS2-1/10 double and AtMRS2-1/5/10 triple knockout lines after selection under increased magnesium supply.
      Title: Magnesium deficiency phenotypes upon multiple knockout of Arabidopsis thaliana MRS2 clade B genes can be ameliorated by concomitantly reduced calcium supply.
    2. AtMGT2/AtMRS2-1 and AtMGT3/AtMRS2-5 were shown to be targeted to the tonoplast and corresponding T-DNA insertion lines had perturbed mesophyll-specific vacuolar magnesium accumulation under serpentine conditions.
      Title: Magnesium transporters, MGT2/MRS2-1 and MGT3/MRS2-5, are important for magnesium partitioning within Arabidopsis thaliana mesophyll vacuoles.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084076.1
    NM_001198078.1
    NM_101469.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables magnesium ion transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within magnesium ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    magnesium transporter 2
    NP_001077545.1
    • magnesium transporter 2 (MGT2); FUNCTIONS IN: magnesium ion transmembrane transporter activity, metal ion transmembrane transporter activity; INVOLVED IN: metal ion transport, transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 32 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mg2+ transporter protein, CorA-like (InterPro:IPR002523); BEST Arabidopsis thaliana protein match is: magnesium transporter 1 (TAIR:AT1G80900.1); Has 790 Blast hits to 772 proteins in 170 species: Archae - 2; Bacteria - 29; Metazoa - 62; Fungi - 196; Plants - 407; Viruses - 0; Other Eukaryotes - 94 (source: NCBI BLink).
    NP_001185007.1
    • magnesium transporter 2 (MGT2); FUNCTIONS IN: magnesium ion transmembrane transporter activity, metal ion transmembrane transporter activity; INVOLVED IN: transmembrane transport, metal ion transport; LOCATED IN: membrane; EXPRESSED IN: 32 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mg2+ transporter protein, CorA-like (InterPro:IPR002523); BEST Arabidopsis thaliana protein match is: magnesium transporter 1 (TAIR:AT1G80900.1).
    NP_563988.1
    • magnesium transporter 2 (MGT2); FUNCTIONS IN: magnesium ion transmembrane transporter activity, metal ion transmembrane transporter activity; INVOLVED IN: metal ion transport, transmembrane transport; LOCATED IN: vacuole, membrane; EXPRESSED IN: 32 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mg2+ transporter protein, CorA-like (InterPro:IPR002523); BEST Arabidopsis thaliana protein match is: magnesium transporter 1 (TAIR:AT1G80900.1); Has 790 Blast hits to 772 proteins in 170 species: Archae - 2; Bacteria - 29; Metazoa - 62; Fungi - 196; Plants - 407; Viruses - 0; Other Eukaryotes - 94 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5495373..5497723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198078.1 → NP_001185007.1  magnesium transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185007.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S9N4
      UniProtKB/TrEMBL
      A0A178WMI6, A0A5S9UPL5
      Conserved Domains (1) summary
      cd12823
      Location:53 → 439
      Mrs2_Mfm1p-like; Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like family

    2. NM_101469.1 → NP_563988.1  magnesium transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563988.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S9N4
      UniProtKB/TrEMBL
      A0A178WMI6, A0A5S9UPL5
      Conserved Domains (1) summary
      cd12823
      Location:53 → 439
      Mrs2_Mfm1p-like; Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like family

    3. NM_001084076.1 → NP_001077545.1  magnesium transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077545.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S9N4
      UniProtKB/TrEMBL
      A0A178WMI6, A0A5S9UPL5
      Conserved Domains (1) summary
      cd12823
      Location:53 → 439
      Mrs2_Mfm1p-like; Saccharomyces cerevisiae inner mitochondrial membrane Mg2+ transporters Mfm1p and Mrs2p-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9S9N4.1

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