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    delta-ADR delta-adaptin [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841298, updated on 18-Sep-2024

    Summary

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    Official Symbol
    delta-ADR
    Official Full Name
    delta-adaptin
    Primary source
    TAIR:AT1G48760
    Locus tag
    AT1G48760
    See related
    Araport:AT1G48760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    delta-adaptin; F11I4.7; F11I4_7; PAT4; PROTEIN-AFFECTED TRAFFICKING 4
    Summary
    Encodes the putative delta subunit of the AP(adaptor protein)-3 complex and plays a role in vacuolar function.
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    Genomic context

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    See delta-ADR in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (18035967..18039405, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene hypothetical protein (DUF1639) Neighboring gene uncharacterized protein Neighboring gene associated molecule with the SH3 domain of STAM 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adaptor Protein-3-Dependent Vacuolar Trafficking Involves a Subpopulation of COPII and HOPS Tethering Proteins. Feng QN, et al. Plant Physiol, 2017 Jul. PMID 28559361, Free PMC Article
    2. The AP-3 adaptor complex is required for vacuolar function in Arabidopsis. Zwiewka M, et al. Cell Res, 2011 Dec. PMID 21670741, Free PMC Article
    3. The ADAPTOR PROTEIN-3 Complex Mediates Pollen Tube Growth by Coordinating Vacuolar Targeting and Organization. Feng QN, et al. Plant Physiol, 2018 May. PMID 29523712, Free PMC Article
    4. EpsinR2 interacts with clathrin, adaptor protein-3, AtVTI12, and phosphatidylinositol-3-phosphate. Implications for EpsinR2 function in protein trafficking in plant cells. Lee GJ, et al. Plant Physiol, 2007 Apr. PMID 17277094, Free PMC Article
    5. Interactomics of Qa-SNARE in Arabidopsis thaliana. Fujiwara M, et al. Plant Cell Physiol, 2014 Apr. PMID 24556609

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A role for AP-3 in pollen tube growth.
      Title: The ADAPTOR PROTEIN-3 Complex Mediates Pollen Tube Growth by Coordinating Vacuolar Targeting and Organization.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036079.1
    NM_103771.2
    NM_179454.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within endosome organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lytic vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein storage vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within vesicle targeting IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of AP-3 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    delta-adaptin
    NP_001031156.1
    • delta-adaptin (delta-ADR); FUNCTIONS IN: protein transporter activity, clathrin binding, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: membrane coat, Golgi apparatus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Adaptor protein complex AP-3, delta subunit (InterPro:IPR017105), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553); BEST Arabidopsis thaliana protein match is: Adaptor protein complex AP-1, gamma subunit (TAIR:AT1G60070.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_175308.1
    • delta-adaptin (delta-ADR); FUNCTIONS IN: protein transporter activity, clathrin binding, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: membrane coat, Golgi apparatus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Adaptor protein complex AP-3, delta subunit (InterPro:IPR017105), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553); BEST Arabidopsis thaliana protein match is: Adaptor protein complex AP-1, gamma subunit (TAIR:AT1G60070.1); Has 3854 Blast hits to 3636 proteins in 331 species: Archae - 0; Bacteria - 22; Metazoa - 1599; Fungi - 800; Plants - 408; Viruses - 0; Other Eukaryotes - 1025 (source: NCBI BLink).
    NP_849785.1
    • delta-adaptin (delta-ADR); FUNCTIONS IN: protein transporter activity, clathrin binding, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: membrane coat, Golgi apparatus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024), Adaptor protein complex AP-3, delta subunit (InterPro:IPR017105), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553); BEST Arabidopsis thaliana protein match is: Adaptor protein complex AP-1, gamma subunit (TAIR:AT1G60070.1); Has 3854 Blast hits to 3636 proteins in 331 species: Archae - 0; Bacteria - 22; Metazoa - 1599; Fungi - 800; Plants - 408; Viruses - 0; Other Eukaryotes - 1025 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18035967..18039405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179454.1 → NP_849785.1  delta-adaptin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849785.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C744
      UniProtKB/TrEMBL
      A0A7G2E2J8
      Conserved Domains (2) summary
      pfam01602
      Location:31 → 482
      Adaptin_N; Adaptin N terminal region
      sd00044
      Location:259 → 286
      HEAT; HEAT repeat [structural motif]

    2. NM_103771.2 → NP_175308.1  delta-adaptin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175308.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C744
      UniProtKB/TrEMBL
      A0A7G2E2J8
      Conserved Domains (2) summary
      pfam01602
      Location:31 → 482
      Adaptin_N; Adaptin N terminal region
      sd00044
      Location:259 → 286
      HEAT; HEAT repeat [structural motif]

    3. NM_001036079.1 → NP_001031156.1  delta-adaptin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031156.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C744
      UniProtKB/TrEMBL
      A0A7G2E2J8
      Conserved Domains (2) summary
      pfam01602
      Location:31 → 482
      Adaptin_N; Adaptin N terminal region
      sd00044
      Location:259 → 286
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C744.1

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