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    RABA1b RAB GTPase homolog A1B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838263, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RABA1b
    Official Full Name
    RAB GTPase homolog A1B
    Primary source
    TAIR:AT1G16920
    Locus tag
    AT1G16920
    See related
    Araport:AT1G16920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRABA1B; BEX5; BFA-visualized exocytic trafficking defective 5; F17F16.26; RAB GTPase homolog A1B; RAB11
    Summary
    small GTP-binding protein (Rab11)similar to YPT3/RAB11 proteins in yeast and mammals, respectively. YPT3/RAB11 is involved in intracellular protein trafficking.
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    Genomic context

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    See RABA1b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (5787150..5789312, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Curculin-like (mannose-binding) lectin family protein Neighboring gene LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640) Neighboring gene uncharacterized protein Neighboring gene F-box/RNI-like/FBD-like domains-containing protein Neighboring gene F-box/RNI-like/FBD-like domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis RABA1 GTPases are involved in transport between the trans-Golgi network and the plasma membrane, and are required for salinity stress tolerance. Asaoka R, et al. Plant J, 2013 Jan. PMID 22974509
    2. BEX5/RabA1b regulates trans-Golgi network-to-plasma membrane protein trafficking in Arabidopsis. Feraru E, et al. Plant Cell, 2012 Jul. PMID 22773752, Free PMC Article
    3. Distinct localization of two closely related Ypt3/Rab11 proteins on the trafficking pathway in higher plants. Inaba T, et al. J Biol Chem, 2002 Mar 15. PMID 11756458
    4. Identification and isoprenylation of plant GTP-binding proteins. Biermann B, et al. Plant Mol Biol, 1996 Aug. PMID 8843944
    5. Null mutants of individual RABA genes impact the proportion of different cell wall components in stem tissue of Arabidopsis thaliana. Lunn D, et al. PLoS One, 2013. PMID 24124508, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Involved in determining the composition of the cell wall, particularly with respect to pectin content, possibly through regulating trafficking of pectin from the Golgi to the apoplast. [RABA1b]
      Title: Null mutants of individual RABA genes impact the proportion of different cell wall components in stem tissue of Arabidopsis thaliana.
    2. Arabidopsis BEX5/RabA1b is a novel regulator of protein trafficking from a trans-Golgi network/early endosomes (TGN/EE) compartment to the plasma membrane.
      Title: BEX5/RabA1b regulates trans-Golgi network-to-plasma membrane protein trafficking in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101553.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within hyperosmotic salinity response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular protein transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of vesicle-mediated transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of vesicle-mediated transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in trans-Golgi network NAS
    Non-traceable Author Statement
    more info
    		  
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog A1B
    NP_173136.1
    • RAB GTPase homolog A1B (RABA1b); FUNCTIONS IN: GTP binding; INVOLVED IN: intracellular protein transport; LOCATED IN: trans-Golgi network, plasma membrane, vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ran GTPase (InterPro:IPR002041), Ras (InterPro:IPR013753), Ras small GTPase, Ras type (InterPro:IPR003577), Rab11-related (InterPro:IPR015595), Small GTPase, Rho type (InterPro:IPR003578), Small GTP-binding protein (InterPro:IPR005225), Ras GTPase (InterPro:IPR001806), Small GTPase (InterPro:IPR020851), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog A1D (TAIR:AT4G18800.1); Has 28198 Blast hits to 28143 proteins in 766 species: Archae - 30; Bacteria - 158; Metazoa - 14550; Fungi - 4232; Plants - 3316; Viruses - 20; Other Eukaryotes - 5892 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5787150..5789312 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101553.3 → NP_173136.1  RAB GTPase homolog A1B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173136.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WSQ7, Q39222, Q8LC05
      UniProtKB/TrEMBL
      A0A178WJV5, A0A5S9US66
      Conserved Domains (1) summary
      cd01868
      Location:11 → 175
      Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39222.1

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