AGL14 AGAMOUS-like 14 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: AGL14
Official Full Name: AGAMOUS-like 14
Primary source: TAIR:AT4G11880
Locus tag: AT4G11880
See related: Araport:AT4G11880
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AGAMOUS-like 14; T26M18.90; T26M18_90; XAANTAL2; XAL2
Summary: AGL12, AGL14, and AGL17 are all preferentially expressed in root tissues and therefore represent the only characterized MADS box genes expressed in roots.
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Genomic context

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See AGL14 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 6

Sequence:: Chromosome: 4; NC_003075.7 (7142922..7147391)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

XAANTAL2 (XAL2/AGL14) is necessary and sufficient to induce flowering, and its regulation is important in floral meristem maintenance and determinacy.
Title: XAANTAL2 (AGL14) Is an Important Component of the Complex Gene Regulatory Network that Underlies Arabidopsis Shoot Apical Meristem Transitions.
The MADS transcription factor XAL2/AGL14 modulates auxin transport during Arabidopsis root development by regulating PIN expression.
Title: The MADS transcription factor XAL2/AGL14 modulates auxin transport during Arabidopsis root development by regulating PIN expression.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001340739.1

Supported by ESTs:

NM_117258.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables transcription cis-regulatory region binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in maintenance of floral meristem identity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in regulation of auxin polar transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of root meristem growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vegetative to reproductive phase transition of meristem	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: AGAMOUS-like 14

NP_001319907.1

AGAMOUS-like 14 (AGL14); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 19 (TAIR:AT4G22950.1); Has 7256 Blast hits to 7253 proteins in 915 species: Archae - 0; Bacteria - 4; Metazoa - 632; Fungi - 309; Plants - 6224; Viruses - 0; Other Eukaryotes - 87 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

7142922..7147391

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001340740.1 → NP_001329521.1 AGAMOUS-like 14 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B7Y6
NM_001340741.1 → NP_001329520.1 AGAMOUS-like 14 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B7Y6
NM_001340739.1 → NP_001319907.1 AGAMOUS-like 14 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0WKU9, Q38838, Q9T056

UniProtKB/TrEMBL

A0A5S9XRQ0
NM_117258.5 → NP_192925.1 AGAMOUS-like 14 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_192925.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0WKU9, Q38838, Q9T056

UniProtKB/TrEMBL

A0A5S9XRQ0

Conserved Domains (2) summary

cd00265
Location:3 → 72

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam01486
Location:85 → 170

K-box; K-box region