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    AR192 Co-chaperone GrpE family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828785, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AR192
    Official Full Name
    Co-chaperone GrpE family protein
    Primary source
    TAIR:AT4G26780
    Locus tag
    AT4G26780
    See related
    Araport:AT4G26780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10M23.120; F10M23_120; MGE2; mitochondrial GrpE 2
    Summary
    unknown function
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    Genomic context

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    See AR192 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (13484839..13486858, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene microtubule-associated protein 65-2 Neighboring gene Phosphatidate cytidylyltransferase family protein Neighboring gene ncRNA Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene SWIB/MDM2 domain superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recent gene duplication and subfunctionalization produced a mitochondrial GrpE, the nucleotide exchange factor of the Hsp70 complex, specialized in thermotolerance to chronic heat stress in Arabidopsis. Hu C, et al. Plant Physiol, 2012 Feb. PMID 22128139, Free PMC Article
    2. Arabidopsis J-protein J20 delivers the first enzyme of the plastidial isoprenoid pathway to protein quality control. Pulido P, et al. Plant Cell, 2013 Oct. PMID 24104567, Free PMC Article
    3. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_118812.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables adenyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper ion binding HDA PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within heat acclimation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in heat acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Co-chaperone GrpE family protein
    NP_567757.1
    • AR192; FUNCTIONS IN: copper ion binding; INVOLVED IN: protein folding, protein import into mitochondrial matrix; LOCATED IN: mitochondrion; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GrpE nucleotide exchange factor (InterPro:IPR000740), GrpE nucleotide exchange factor, head (InterPro:IPR009012), GrpE nucleotide exchange factor, coiled-coil (InterPro:IPR013805); BEST Arabidopsis thaliana protein match is: Co-chaperone GrpE family protein (TAIR:AT5G55200.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13484839..13486858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118812.4 → NP_567757.1  Co-chaperone GrpE family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567757.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LB47, Q96515, Q9SZ18
      UniProtKB/TrEMBL
      A0A178V1B9, A0A5S9XX21
      Conserved Domains (1) summary
      cd00446
      Location:163 → 312
      GrpE; nucleotide exchange factor GrpE
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LB47.1

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