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    IPMI1 isopropylmalate isomerase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825068, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IPMI1
    Official Full Name
    isopropylmalate isomerase 1
    Primary source
    TAIR:AT3G58990
    Locus tag
    AT3G58990
    See related
    Araport:AT3G58990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    isopropylmalate isomerase 1
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    Genomic context

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    See IPMI1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (21797058..21798303, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene F-box family protein Neighboring gene F-box/RNI-like superfamily protein Neighboring gene pectin methylesterase 61

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Arabidopsis thaliana Substrate Recognition and Tissue- as Well as Plastid Type-Specific Expression Define the Roles of Distinct Small Subunits of Isopropylmalate Isomerase. Lächler K, et al. Front Plant Sci, 2020. PMID 32612621, Free PMC Article
    2. Functional specification of Arabidopsis isopropylmalate isomerases in glucosinolate and leucine biosynthesis. He Y, et al. Plant Cell Physiol, 2010 Sep. PMID 20663849
    3. The plastidic bile acid transporter 5 is required for the biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana. Gigolashvili T, et al. Plant Cell, 2009 Jun. PMID 19542295, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_115761.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-isopropylmalate dehydratase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-leucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glucosinolate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    isopropylmalate isomerase 1
    NP_191458.1
    • isopropylmalate isomerase 1 (IPMI1); FUNCTIONS IN: hydro-lyase activity, 3-isopropylmalate dehydratase activity; INVOLVED IN: leucine biosynthetic process, metabolic process; LOCATED IN: plastid; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: 3-isopropylmalate dehydratase, small subunit-like (InterPro:IPR012305), Aconitase A/isopropylmalate dehydratase small subunit, swivel (InterPro:IPR000573), Aconitase/3-isopropylmalate dehydratase, swivel (InterPro:IPR015928), Aconitase-like core (InterPro:IPR015937); BEST Arabidopsis thaliana protein match is: Aconitase/3-isopropylmalate dehydratase protein (TAIR:AT2G43090.1); Has 8940 Blast hits to 8939 proteins in 2288 species: Archae - 372; Bacteria - 5509; Metazoa - 6; Fungi - 358; Plants - 71; Viruses - 0; Other Eukaryotes - 2624 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      21797058..21798303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115761.3 → NP_191458.1  isopropylmalate isomerase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191458.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LYT7
      UniProtKB/TrEMBL
      A0A178VAQ3, A0A5S9XNV5, A0A654FJ39
      Conserved Domains (1) summary
      PLN00072
      Location:1 → 253
      PLN00072; 3-isopropylmalate isomerase/dehydratase small subunit; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LYT7.1

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