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    ACR12 ACT domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830352, updated on 18-Sep-2024

    Summary

    Official Symbol
    ACR12
    Official Full Name
    ACT domain-containing protein
    Primary source
    TAIR:AT5G04740
    Locus tag
    AT5G04740
    See related
    Araport:AT5G04740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ACT domain repeats 12; MUK11.6
    Summary
    Encodes a ACT domain-containing protein. The ACT domain, named after bacterial aspartate kinase, chorismate mutase and TyrA (prephenate dehydrogenase), is a regulatory domain that serves as an amino acid-binding site in feedback-regulated amino acid metabolic enzymes.
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    Genomic context

    See ACR12 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (1367911..1371550, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ADR1-like 2 Neighboring gene Ankyrin-repeat containing protein Neighboring gene F1F0-ATPase inhibitor protein Neighboring gene Duplicated homeodomain-like superfamily protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    ACT domain-containing protein
    NP_001190227.1
    • ACT domain-containing protein; FUNCTIONS IN: amino acid binding; INVOLVED IN: metabolic process; LOCATED IN: chloroplast thylakoid membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Amino acid-binding ACT (InterPro:IPR002912); BEST Arabidopsis thaliana protein match is: uridylyltransferase-related (TAIR:AT1G16880.1).
    NP_196094.1
    • ACT domain-containing protein; FUNCTIONS IN: amino acid binding; INVOLVED IN: metabolic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast stroma, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Amino acid-binding ACT (InterPro:IPR002912); BEST Arabidopsis thaliana protein match is: uridylyltransferase-related (TAIR:AT1G16880.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1367911..1371550 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120556.3NP_196094.1  ACT domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196094.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LB85, Q9LZ23
      UniProtKB/TrEMBL
      A0A178UNY1, A0A5S9Y1F1
      Conserved Domains (2) summary
      cd04873
      Location:223288
      ACT_UUR-ACR-like; ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD
      PRK03381
      Location:91145
      PRK03381; PII uridylyl-transferase; Provisional
    2. NM_001203298.1NP_001190227.1  ACT domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190227.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JXP5
      Conserved Domains (1) summary
      cd04873
      Location:122187
      ACT_UUR-ACR-like; ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD