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    forkhead-associated domain-containing protein / FHA domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830631, updated on 18-Sep-2024

    Summary

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    Official Full Name
    forkhead-associated domain-containing protein / FHA domain-containing protein
    Primary source
    TAIR:AT5G07400
    Locus tag
    AT5G07400
    See related
    Araport:AT5G07400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T2I1.110; T2I1_110
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (2340623..2345545)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Amidase family protein Neighboring gene inositol polyphosphate kinase 2 alpha Neighboring gene uncharacterized protein Neighboring gene respiratory burst oxidase homolog A Neighboring gene Pectin lyase-like superfamily protein Neighboring gene Pectin lyase-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development. Yamaoka S, et al. Plant Cell, 2013 Aug. PMID 23975897, Free PMC Article
    2. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001342937.1
    NM_001342938.1
    NM_001342939.1
    NM_001342940.1
    NM_001342941.1
    NM_001342942.1
    NM_001342943.1
    NM_120822.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    forkhead-associated domain-containing protein / FHA domain-containing protein
    NP_196357.2
    • forkhead-associated domain-containing protein / FHA domain-containing protein; FUNCTIONS IN: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, phosphoric diester hydrolase activity, zinc ion binding, nucleic acid binding; INVOLVED IN: DNA repair; LOCATED IN: nucleus; EXPRESSED IN: sperm cell, seed; EXPRESSED DURING: F mature embryo stage; CONTAINS InterPro DOMAIN/s: Tyrosyl-DNA phosphodiesterase (InterPro:IPR010347), SMAD/FHA domain (InterPro:IPR008984), Forkhead-associated (FHA) domain (InterPro:IPR000253), HIP116, Rad5p N-terminal (InterPro:IPR014905); BEST Arabidopsis thaliana protein match is: tyrosyl-DNA phosphodiesterase-related (TAIR:AT5G15170.1); Has 394 Blast hits to 361 proteins in 119 species: Archae - 0; Bacteria - 2; Metazoa - 165; Fungi - 89; Plants - 76; Viruses - 0; Other Eukaryotes - 62 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2340623..2345545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120822.5 → NP_196357.2  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196357.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y272, A0A654FZC6, Q84MA4
      Conserved Domains (4) summary
      cd09122
      Location:385 → 551
      PLDc_Tdp1_1; Catalytic domain, repeat 1, of Tyrosyl-DNA phosphodiesterase
      cd09123
      Location:772 → 972
      PLDc_Tdp1_2; Catalytic domain, repeat 2, of tyrosyl-DNA phosphodiesterase
      cd00060
      Location:19 → 142
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam08797
      Location:611 → 734
      HIRAN; HIRAN domain

    2. NM_001342937.1 → NP_001332337.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGL9, A0A7G2F6A2

    3. NM_001342938.1 → NP_001332339.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGM0

    4. NM_001342939.1 → NP_001332334.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGL5, A0A5S9Y272

    5. NM_001342942.1 → NP_001332335.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGL5, A0A5S9Y272

    6. NM_001342943.1 → NP_001332338.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGL6, A0A5S9Y272

    7. NM_001342940.1 → NP_001332333.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGM0

    8. NM_001342941.1 → NP_001332336.1  forkhead-associated domain-containing protein / FHA domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BGL7
    Nucleotide Protein
    Heading Accession and Version

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