CESA5 cellulose synthase 5 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CESA5
Official Full Name: cellulose synthase 5
Primary source: TAIR:AT5G09870
Locus tag: AT5G09870
See related: Araport:AT5G09870
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: cellulose synthase 5; MUCILAGE-MODIFIED 3; MUM3; MYH9.8; MYH9_8
Summary: Encodes a cellulose synthase CESA5 that produces seed mucilage cellulose.
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Genomic context

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See CESA5 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 13

Sequence:: Chromosome: 5; NC_003076.8 (3072870..3078416)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Five amino acid mismatches in the zinc-finger domains of Cellulose Synthase 5 and Cellulose Synthase 6 cooperatively modulate their functional properties by controlling homodimerization in Arabidopsis.
Title: Five amino acid mismatches in the zinc-finger domains of Cellulose Synthase 5 and Cellulose Synthase 6 cooperatively modulate their functional properties by controlling homodimerization in Arabidopsis.
Mutations in CELLULOSE SYNTHASE 5 also led to reduced rays and mal-partitioning of the pectic component of seed mucilage, further establishing a structural role for cellulose in seed mucilage.
Title: The FEI2-SOS5 pathway and CELLULOSE SYNTHASE 5 are required for cellulose biosynthesis in the Arabidopsis seed coat and affect pectin mucilage structure.
The data indicate that CESA5-derived cellulose plays an important role in the synthesis and structure of seed coat mucilage and that the FEI2/SOS5 pathway plays a role in the regulation of cellulose synthesis in MSCs.
Title: Cellulose synthesis via the FEI2 RLK/SOS5 pathway and cellulose synthase 5 is required for the structure of seed coat mucilage in Arabidopsis.
CESA5 plays a major and essential role in cellulose production in seed mucilage.
Title: CESA5 is required for the synthesis of cellulose with a role in structuring the adherent mucilage of Arabidopsis seeds.
only CESA5 and XTH17 were affected by the gl2 mutation.
Title: The GLABRA2 homeodomain protein directly regulates CESA5 and XTH17 gene expression in Arabidopsis roots.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_121024.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables cellulose synthase (UDP-forming) activity	IEA Inferred from Electronic Annotation more info
enables cellulose synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables glycosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellulose biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mucilage biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mucilage biosynthetic process involved in seed coat development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in plant-type cell wall biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within plant-type cell wall biogenesis	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	HDA more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info
located_in plasma membrane	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: cellulose synthase 5

NP_196549.1

cellulose synthase 5 (CESA5); FUNCTIONS IN: cellulose synthase activity, transferase activity, transferring glycosyl groups; INVOLVED IN: response to cyclopentenone, plant-type cell wall biogenesis; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cellulose synthase (InterPro:IPR005150), Zinc finger, RING-type (InterPro:IPR001841); BEST Arabidopsis thaliana protein match is: cellulose synthase 6 (TAIR:AT5G64740.1); Has 3218 Blast hits to 2905 proteins in 647 species: Archae - 9; Bacteria - 1207; Metazoa - 1; Fungi - 23; Plants - 1882; Viruses - 5; Other Eukaryotes - 91 (source: NCBI BLink).