U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Translation elongation factor EF1A/initiation factor IF2gamma family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830928, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    Translation elongation factor EF1A/initiation factor IF2gamma family protein
    Primary source
    TAIR:AT5G10630
    Locus tag
    AT5G10630
    See related
    Araport:AT5G10630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12B17.20; F12B17_20
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (3359832..3364623)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 81, subfamily K, polypeptide 1 Neighboring gene methyltransferase Neighboring gene flowering-promoting factor-like protein Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. PELOTA and HBS1 suppress co-translational messenger RNA decay in Arabidopsis. Guo R, et al. Plant Direct, 2023 Dec. PMID 38149303, Free PMC Article
    2. mRNA surveillance complex PELOTA-HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth. Kong W, et al. Plant Physiol, 2021 Aug 3. PMID 33930167, Free PMC Article
    3. The No-go decay system degrades plant mRNAs that contain a long A-stretch in the coding region. Szádeczky-Kardoss I, et al. Plant Sci, 2018 Oct. PMID 30107878
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. mRNA surveillance complex PELOTA-HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth.
      Title: mRNA surveillance complex PELOTA-HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help
    NM_001343127.1
    NM_121101.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of mRNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, non-stop decay IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Translation elongation factor EF1A/initiation factor IF2gamma family protein
    NP_001190282.1
    • Translation elongation factor EF1A/initiation factor IF2gamma family protein; FUNCTIONS IN: GTP binding, translation elongation factor activity, GTPase activity, zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Translation elongation factor EFTu/EF1A, C-terminal (InterPro:IPR004160), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (InterPro:IPR009001), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Zinc finger, RanBP2-type (InterPro:IPR001876), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: Translation elongation factor EF1A/initiation factor IF2gamma family protein (TAIR:AT1G18070.2).
    NP_196625.2
    • Translation elongation factor EF1A/initiation factor IF2gamma family protein; FUNCTIONS IN: GTP binding, translation elongation factor activity, GTPase activity, zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Translation elongation factor EFTu/EF1A, C-terminal (InterPro:IPR004160), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (InterPro:IPR009001), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Zinc finger, RanBP2-type (InterPro:IPR001876), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: Translation elongation factor EF1A/initiation factor IF2gamma family protein (TAIR:AT1G18070.2); Has 86905 Blast hits to 86827 proteins in 18414 species: Archae - 1008; Bacteria - 36763; Metazoa - 20627; Fungi - 12842; Plants - 2029; Viruses - 6; Other Eukaryotes - 13630 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3359832..3364623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343125.1 → NP_001331941.1  Translation elongation factor EF1A/initiation factor IF2gamma family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFE6, A0A7G2F6I9

    2. NM_001203353.2 → NP_001190282.1  Translation elongation factor EF1A/initiation factor IF2gamma family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190282.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y322, F4KI84
      Conserved Domains (5) summary
      smart00547
      Location:51 → 73
      ZnF_RBZ; Zinc finger domain
      cd01883
      Location:242 → 462
      EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family
      COG5256
      Location:241 → 664
      TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]
      cd16267
      Location:468 → 552
      HBS1-like_II; Domain II of Hbs1-like proteins
      cd04093
      Location:556 → 664
      HBS1_C_III; C-terminal domain of Hsp70 subfamily B suppressor 1 (HBS1)

    3. NM_001343126.1 → NP_001331942.1  Translation elongation factor EF1A/initiation factor IF2gamma family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFF4, A0A7G2F6I9

    4. NM_121101.3 → NP_196625.2  Translation elongation factor EF1A/initiation factor IF2gamma family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196625.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y322, B9DFA5
      Conserved Domains (5) summary
      smart00547
      Location:50 → 72
      ZnF_RBZ; Zinc finger domain
      cd01883
      Location:241 → 461
      EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family
      COG5256
      Location:240 → 663
      TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]
      cd16267
      Location:467 → 551
      HBS1-like_II; Domain II of Hbs1-like proteins
      cd04093
      Location:555 → 663
      HBS1_C_III; C-terminal domain of Hsp70 subfamily B suppressor 1 (HBS1)

    5. NM_001343127.1 → NP_001331943.1  Translation elongation factor EF1A/initiation factor IF2gamma family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y322, F4KI84
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.