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    NCLPP7 nuclear-encoded CLP protease P7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832378, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NCLPP7
    Official Full Name
    nuclear-encoded CLP protease P7
    Primary source
    TAIR:AT5G23140
    Locus tag
    AT5G23140
    See related
    Araport:AT5G23140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CLPP2; MYJ24.13; MYJ24_13; nuclear-encoded CLP protease P7
    Summary
    One of several nuclear-encoded ClpPs (caseinolytic protease). Contains a highly conserved catalytic triad of Ser-type proteases (Ser-His-Asp). The name reflects nomenclature described in Adam et. al (2001).
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    Genomic context

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    See NCLPP7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (7783673..7785547)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene photosystem II stability/assembly factor, chloroplast (HCF136) Neighboring gene Peptidoglycan-binding LysM domain-containing protein Neighboring gene Tudor/PWWP/MBT domain-containing protein Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial CLPP2 Assists Coordination and Homeostasis of Respiratory Complexes. Petereit J, et al. Plant Physiol, 2020 Sep. PMID 32571844, Free PMC Article
    2. Plant mitochondria contain proteolytic and regulatory subunits of the ATP-dependent Clp protease. Halperin T, et al. Plant Mol Biol, 2001 Mar. PMID 11352464
    3. Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana. Peltier JB, et al. J Biol Chem, 2001 May 11. PMID 11278690
    4. Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications. Peltier JB, et al. J Biol Chem, 2004 Feb 6. PMID 14593120
    5. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_122220.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP-dependent peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cobalt ion binding HDA PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding HDA PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast thylakoid membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of chloroplastic endopeptidase Clp complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 
    located_in plastid stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear-encoded CLP protease P7
    NP_568427.1
    • nuclear-encoded CLP protease P7 (NCLPP7); FUNCTIONS IN: cobalt ion binding, zinc ion binding; INVOLVED IN: proteolysis; LOCATED IN: in 6 components; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S14, ClpP, active site (InterPro:IPR018215), Peptidase S14, ClpP (InterPro:IPR001907); BEST Arabidopsis thaliana protein match is: nuclear encoded CLP protease 5 (TAIR:AT1G02560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7783673..7785547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122220.5 → NP_568427.1  nuclear-encoded CLP protease P7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568427.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FN42
      UniProtKB/TrEMBL
      A0A178U8I8, A0A5S9Y6F8, A0A7G2F9Q6
      Conserved Domains (1) summary
      PRK00277
      Location:31 → 225
      clpP; ATP-dependent Clp protease proteolytic subunit; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FN42.1

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