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    KCO3 Ca2+ activated outward rectifying K+ channel 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834679, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KCO3
    Official Full Name
    Ca2+ activated outward rectifying K+ channel 3
    Primary source
    TAIR:AT5G46360
    Locus tag
    AT5G46360
    See related
    Araport:AT5G46360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATKCO3; Ca2+ activated outward rectifying K+ channel 3; CA2+ ACTIVATED OUTWARD RECTIFYING K+ CHANNEL 3; MPL12.16; MPL12_16
    Summary
    Encodes AtKCO3, a member of the Arabidopsis thaliana K+ channel family of AtTPK/KCO proteins. AtKCO3 is targeted to the vacuolar membrane. Forms homomeric ion channels in vivo.
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    Genomic context

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    See KCO3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (18806563..18808224, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene WRKY DNA-binding protein 8 Neighboring gene ncRNA Neighboring gene Ca2+ activated outward rectifying K+ channel 2 Neighboring gene Serine/Threonine-kinase, putative (DUF1296)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of Arabidopsis TPK2 and KCO3 reveals structural properties required for K(+) channel function. Uehara C, et al. Channels (Austin), 2020 Dec. PMID 33016199, Free PMC Article
    2. Members of the Arabidopsis AtTPK/KCO family form homomeric vacuolar channels in planta. Voelker C, et al. Plant J, 2006 Oct. PMID 16984403
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Analysis of Arabidopsis TPK2 and KCO3 reveals structural properties required for K(+) channel function.
      Title: Analysis of Arabidopsis TPK2 and KCO3 reveals structural properties required for K(+) channel function.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ca2+ activated outward rectifying K+ channel 3
    NP_001190480.1
    • Ca2+ activated outward rectifying K+ channel 3 (KCO3); FUNCTIONS IN: outward rectifier potassium channel activity, calcium ion binding; INVOLVED IN: protein homooligomerization; LOCATED IN: plant-type vacuole membrane; EXPRESSED IN: hydathode, vascular tissue, root, flower, leaf; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Ion transport 2 (InterPro:IPR013099); BEST Arabidopsis thaliana protein match is: Ca2+ activated outward rectifying K+ channel 2 (TAIR:AT5G46370.1).
    NP_199448.1
    • Ca2+ activated outward rectifying K+ channel 3 (KCO3); CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Ion transport 2 (InterPro:IPR013099); BEST Arabidopsis thaliana protein match is: Ca2+ activated outward rectifying K+ channel 2 (TAIR:AT5G46370.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18806563..18808224 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203551.1 → NP_001190480.1  Ca2+ activated outward rectifying K+ channel 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190480.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G8J8
      Conserved Domains (1) summary
      pfam07885
      Location:104 → 176
      Ion_trans_2; Ion channel

    2. NM_124006.3 → NP_199448.1  Ca2+ activated outward rectifying K+ channel 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199448.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KHG2, Q9XFR0
      UniProtKB/TrEMBL
      A0A5S9YBI5, A0A654G8J8
      Conserved Domains (2) summary
      pfam07885
      Location:104 → 176
      Ion_trans_2; Ion channel
      pfam13499
      Location:199 → 259
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XFR0.1

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