U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nxph1 neurexophilin 1 [ Mus musculus (house mouse) ]

    Gene ID: 18231, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nxph1provided by MGI
    Official Full Name
    neurexophilin 1provided by MGI
    Primary source
    MGI:MGI:107492
    See related
    Ensembl:ENSMUSG00000046178 AllianceGenome:MGI:107492
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C130005L03Rik
    Summary
    Enables signaling receptor binding activity. Involved in modulation of chemical synaptic transmission. Is active in GABA-ergic synapse; glutamatergic synapse; and synaptic cleft. Is expressed in brain; metanephros; and spinal cord mantle layer. Orthologous to human NXPH1 (neurexophilin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 2.9), frontal lobe adult (RPKM 2.6) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nxph1 in Genome Data Viewer
    Location:
    6 A1; 6 4.38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (8948154..9259863)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (8948614..9249619)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38765 Neighboring gene STARR-seq mESC enhancer starr_15127 Neighboring gene predicted gene, 35674 Neighboring gene STARR-seq mESC enhancer starr_15129 Neighboring gene STARR-seq mESC enhancer starr_15130 Neighboring gene STARR-seq mESC enhancer starr_15131 Neighboring gene STARR-seq mESC enhancer starr_15132 Neighboring gene STARR-seq mESC enhancer starr_15133 Neighboring gene STARR-seq mESC enhancer starr_15134 Neighboring gene STARR-seq mESC enhancer starr_15135 Neighboring gene STARR-seq mESC enhancer starr_15136 Neighboring gene STARR-seq mESC enhancer starr_15137 Neighboring gene nuclear encoded tRNA valine 5 (anticodon CAC) Neighboring gene actin, gamma, cytoplasmic 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008751.5NP_032777.3  neurexophilin-1 precursor

      See identical proteins and their annotated locations for NP_032777.3

      Status: PROVISIONAL

      Source sequence(s)
      BC145955
      Consensus CDS
      CCDS39426.1
      UniProtKB/Swiss-Prot
      A6H6P7, Q61200, Q8BHJ2, Q8BLP4
      UniProtKB/TrEMBL
      Q3TQN5
      Related
      ENSMUSP00000060926.4, ENSMUST00000060369.4
      Conserved Domains (1) summary
      pfam06312
      Location:66271
      Neurexophilin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      8948154..9259863
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505010.5XP_006505073.1  neurexophilin-1 isoform X2

      See identical proteins and their annotated locations for XP_006505073.1

      UniProtKB/Swiss-Prot
      A6H6P7, Q61200, Q8BHJ2, Q8BLP4
      UniProtKB/TrEMBL
      Q3TQN5
      Related
      ENSMUSP00000125274.2, ENSMUST00000160300.2
      Conserved Domains (1) summary
      pfam06312
      Location:66271
      Neurexophilin
    2. XM_036165922.1XP_036021815.1  neurexophilin-1 isoform X1

      UniProtKB/TrEMBL
      Q3TQN5
      Conserved Domains (1) summary
      pfam06312
      Location:68273
      Neurexophilin