Slc35g1 solute carrier family 35, member G1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Slc35g1provided by MGI
Official Full Name: solute carrier family 35, member G1provided by MGI
Primary source: MGI:MGI:2444789
See related: Ensembl:ENSMUSG00000044026 AllianceGenome:MGI:2444789
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Tmem20; D330039I19Rik
Summary: Predicted to be involved in calcium ion export across plasma membrane and regulation of cytosolic calcium ion concentration. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Is expressed in eye; genitourinary system; gut; nervous system; and trachea. Orthologous to human SLC35G1 (solute carrier family 35 member G1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in bladder adult (RPKM 16.2), large intestine adult (RPKM 13.1) and 17 other tissues See more
Orthologs: human all
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Genomic context

Location:: 19 C3; 19 33.03 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (38384428..38394055)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (38395980..38405607)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Discovery and Validation of Novel Genes in a Large Chinese Autism Spectrum Disorder Cohort.
Title: Discovery and Validation of Novel Genes in a Large Chinese Autism Spectrum Disorder Cohort.
Study shows that microRNA-150 modulates intracellular Ca (2+) levels in naive CD8(+) T cells by targeting transmembrane protein 20.
Title: MicroRNA-150 modulates intracellular Ca (2+) levels in naïve CD8(+) T cells by targeting TMEM20.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in calcium ion export across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in calcium ion export across plasma membrane	IEA Inferred from Electronic Annotation more info
involved_in calcium ion export across plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in regulation of cytosolic calcium ion concentration	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info
involved_in regulation of cytosolic calcium ion concentration	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: solute carrier family 35 member G1

Names: transmembrane protein 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175507.3 → NP_780716.1 solute carrier family 35 member G1

See identical proteins and their annotated locations for NP_780716.1

Status: VALIDATED

Source sequence(s)

AC116871, AC124632

Consensus CDS

CCDS29787.1

UniProtKB/Swiss-Prot

B2RPY9, Q8BY79

Related

ENSMUSP00000061282.3, ENSMUST00000054098.4

Conserved Domains (2) summary

COG0697
Location:73 → 362

RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]

pfam00892
Location:72 → 205

EamA; EamA-like transporter family