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    Adh6a alcohol dehydrogenase 6A (class V) [ Mus musculus (house mouse) ]

    Gene ID: 69117, updated on 9-Dec-2024

    Summary

    Official Symbol
    Adh6aprovided by MGI
    Official Full Name
    alcohol dehydrogenase 6A (class V)provided by MGI
    Primary source
    MGI:MGI:1916367
    See related
    Ensembl:ENSMUSG00000053054 AllianceGenome:MGI:1916367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Adh5a; 1810009C16Rik
    Summary
    Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity and zinc ion binding activity. Predicted to be involved in retinoic acid metabolic process and retinol metabolic process. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in duodenum adult (RPKM 44.5), small intestine adult (RPKM 35.6) and 1 other tissue See more
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    Genomic context

    See Adh6a in Genome Data Viewer
    Location:
    3 G3; 3 64.19 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (138019047..138036895)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (138313286..138331134)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene Adh1 promoter region Neighboring gene alcohol dehydrogenase 1 (class I) Neighboring gene predicted gene 16559 Neighboring gene predicted gene, 23467 Neighboring gene alcohol dehydrogenase 6B (class V) Neighboring gene alcohol dehydrogenase 6 (class V), pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables alcohol dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables all-trans-retinol dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in retinoic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retinol metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    alcohol dehydrogenase 6A (class V)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026945.1NP_081221.1  alcohol dehydrogenase 6A (class V)

      Status: VALIDATED

      Source sequence(s)
      AK007397, AK028114, BB870350
      Consensus CDS
      CCDS38652.1
      UniProtKB/TrEMBL
      A1L3C0, E9Q5Z6
      Related
      ENSMUSP00000101854.2, ENSMUST00000106247.2
      Conserved Domains (2) summary
      COG1062
      Location:8375
      FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
      cl16912
      Location:3375
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      138019047..138036895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)