TGG2 glucoside glucohydrolase 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: TGG2
Official Full Name: glucoside glucohydrolase 2
Primary source: TAIR:AT5G25980
Locus tag: AT5G25980
See related: Araport:AT5G25980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: BETA GLUCOSIDASE 37; BGLU37; glucoside glucohydrolase 2; T1N24.18; T1N24_18
Summary: Myrosinase (thioglucoside glucohydrolase) gene involved in glucosinoloate metabolism.
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Genomic context

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See TGG2 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 12

Sequence:: Chromosome: 5; NC_003076.8 (9072708..9075777)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Imaging of Guard Cells of thioglucosidase (tgg) Mutants of Arabidopsis Further Links Plant Chemical Defence Systems with Physical Defence Barriers.
Title: The Imaging of Guard Cells of thioglucosidase (tgg) Mutants of Arabidopsis Further Links Plant Chemical Defence Systems with Physical Defence Barriers.
The Myrosinases TGG1 and TGG2 Function Redundantly in Reactive Carbonyl Species Signaling in Arabidopsis Guard Cells.
Title: The Myrosinases TGG1 and TGG2 Function Redundantly in Reactive Carbonyl Species Signaling in Arabidopsis Guard Cells.
The tgg1, single and tgg1 tgg2 double mutants showed morphological changes compared to wild-type plants visible as changes in pavement cells, stomatal cells and the ultrastructure of the cuticle.
Title: Arabidopsis myrosinases link the glucosinolate-myrosinase system and the cuticle.
Data indicate that loss of the basic helix-loop-helix transcription factor FAMA function abolishes myrosin idioblasts (MIs) fate as well as the expression of the myrosinase genes TGG1 and TGG2.
Title: Myrosin idioblast cell fate and development are regulated by the Arabidopsis transcription factor FAMA, the auxin pathway, and vesicular trafficking.
These results demonstrate that TGG1 and TGG2 have the ability to function in environments like the digestive tract of insect herbivores that are significantly different from the environment in a damaged plant.
Title: Properties of β-thioglucoside hydrolases (TGG1 and TGG2) from leaves of Arabidopsis thaliana.
It was suggested that propose that MVP1 is a myrosinase-associated protein that functions, in part, to correctly localize the myrosinase TGG2 and prevent inappropriate glucosinolate hydrolysis that could generate cytotoxic molecules.
Title: MODIFIED VACUOLE PHENOTYPE1 is an Arabidopsis myrosinase-associated protein involved in endomembrane protein trafficking.
TGG1 and TGG2 function redundantly downstream of ROS production and upstream of cytosolic Ca2+ elevation in abscisic acid and methyl jasmonate signaling in guard cells.
Title: Myrosinases, TGG1 and TGG2, redundantly function in ABA and MeJA signaling in Arabidopsis guard cells.
Arabidopsis myrosinases TGG1 and TGG2 are functionally redundant.
Title: Arabidopsis myrosinases TGG1 and TGG2 have redundant function in glucosinolate breakdown and insect defense.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001036863.1

Supported by ESTs:

NM_122499.4

Supported by ESTs:

NM_180745.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables thioglucosidase activity	IEA Inferred from Electronic Annotation more info
enables thioglucosidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables thioglucosidase activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in defense response to insect	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within glucosinolate catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within glucosinolate catabolic process	NAS Non-traceable Author Statement more info	PubMed
involved_in regulation of stomatal movement	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in apoplast	HDA more info	PubMed
located_in chloroplast	HDA more info	PubMed
located_in cytosolic ribosome	HDA more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in peroxisome	HDA more info	PubMed
located_in plant-type vacuole	HDA more info	PubMed
located_in plasmodesma	HDA more info	PubMed
located_in plastid	HDA more info	PubMed
located_in secretory vesicle	HDA more info	PubMed

General protein information

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Preferred Names: glucoside glucohydrolase 2

NP_001031940.1

glucoside glucohydrolase 2 (TGG2); FUNCTIONS IN: thioglucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds; INVOLVED IN: glucosinolate catabolic process; LOCATED IN: cytosolic ribosome, apoplast, chloroplast, peroxisome, vacuole; EXPRESSED IN: phloem, vascular bundle, fruit, guard cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 1 (InterPro:IPR001360), Glycoside hydrolase, family 1, active site (InterPro:IPR018120), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: thioglucoside glucohydrolase 1 (TAIR:AT5G26000.1); Has 10736 Blast hits to 10485 proteins in 1462 species: Archae - 125; Bacteria - 7652; Metazoa - 685; Fungi - 198; Plants - 1368; Viruses - 0; Other Eukaryotes - 708 (source: NCBI BLink).

NP_568479.1

glucoside glucohydrolase 2 (TGG2); FUNCTIONS IN: thioglucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds; INVOLVED IN: glucosinolate catabolic process; LOCATED IN: cytosolic ribosome, apoplast, peroxisome, chloroplast, vacuole; EXPRESSED IN: phloem, vascular bundle, fruit, guard cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 1 (InterPro:IPR001360), Glycoside hydrolase, family 1, active site (InterPro:IPR018120), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: thioglucoside glucohydrolase 1 (TAIR:AT5G26000.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NP_851076.2

glucoside glucohydrolase 2 (TGG2); FUNCTIONS IN: thioglucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds; INVOLVED IN: glucosinolate catabolic process; LOCATED IN: cytosolic ribosome, apoplast, peroxisome, chloroplast, vacuole; EXPRESSED IN: phloem, vascular bundle, fruit, guard cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 1 (InterPro:IPR001360), Glycoside hydrolase, family 1, active site (InterPro:IPR018120), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: thioglucoside glucohydrolase 1 (TAIR:AT5G26000.1); Has 10736 Blast hits to 10485 proteins in 1462 species: Archae - 125; Bacteria - 7652; Metazoa - 685; Fungi - 198; Plants - 1368; Viruses - 0; Other Eukaryotes - 708 (source: NCBI BLink).