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    phosphoesterase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820718, updated on 18-Sep-2024

    Summary

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    Official Full Name
    phosphoesterase
    Primary source
    TAIR:AT3G14890
    Locus tag
    AT3G14890
    See related
    Araport:AT3G14890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    17
    Sequence:
    Chromosome: 3; NC_003074.8 (5008676..5013265)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF641) Neighboring gene transcription factor-like protein Neighboring gene uncharacterized protein Neighboring gene Rab3 GTPase-activating protein non-catalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. APURINIC/APYRIMIDINIC ENDONUCLEASE2 and ZINC FINGER DNA 3'-PHOSPHOESTERASE Play Overlapping Roles in the Maintenance of Epigenome and Genome Stability. Li J, et al. Plant Cell, 2018 Sep. PMID 30135084, Free PMC Article
    2. A DNA 3' phosphatase functions in active DNA demethylation in Arabidopsis. Martínez-Macías MI, et al. Mol Cell, 2012 Feb 10. PMID 22325353, Free PMC Article
    3. The DNA repair protein XRCC1 functions in the plant DNA demethylation pathway by stimulating cytosine methylation (5-meC) excision, gap tailoring, and DNA ligation. Martínez-Macías MI, et al. J Biol Chem, 2013 Feb 22. PMID 23316050, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112351.4
    NM_180255.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables polynucleotide 3'-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phosphoesterase
    NP_188107.3
    • phosphoesterase; FUNCTIONS IN: DNA binding, catalytic activity, zinc ion binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HAD-superfamily hydrolase, subfamily IIIA (InterPro:IPR006549), Polynucleotide kinase 3 phosphatase, central region (InterPro:IPR013954), Zinc finger, PARP-type (InterPro:IPR001510), Polynucleotide kinase 3, phosphatase (InterPro:IPR015636), DNA 3-phosphatase (InterPro:IPR006551); BEST Arabidopsis thaliana protein match is: poly(ADP-ribose) polymerase 2 (TAIR:AT2G31320.1); Has 2061 Blast hits to 1425 proteins in 265 species: Archae - 2; Bacteria - 49; Metazoa - 943; Fungi - 202; Plants - 219; Viruses - 45; Other Eukaryotes - 601 (source: NCBI BLink).
    NP_850586.2
    • phosphoesterase; FUNCTIONS IN: DNA binding, catalytic activity, zinc ion binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HAD-superfamily hydrolase, subfamily IIIA (InterPro:IPR006549), Polynucleotide kinase 3 phosphatase, central region (InterPro:IPR013954), Zinc finger, PARP-type (InterPro:IPR001510), Polynucleotide kinase 3, phosphatase (InterPro:IPR015636), DNA 3-phosphatase (InterPro:IPR006551); BEST Arabidopsis thaliana protein match is: poly(ADP-ribose) polymerase 2 (TAIR:AT2G31320.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5008676..5013265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112351.4 → NP_188107.3  phosphoesterase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188107.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IXD6, Q84JE8, Q8LL89, Q9LKB5
      UniProtKB/TrEMBL
      A0A178VCN9
      Conserved Domains (3) summary
      PLN03123
      Location:49 → 353
      PLN03123; poly [ADP-ribose] polymerase; Provisional
      cd01625
      Location:521 → 685
      HAD_PNP; polynucleotide 3'-phosphatase domain similar to the phosphatase domain of the bifunctional enzyme polynucleotide 5'-kinase/3'-phosphatase
      pfam00645
      Location:331 → 406
      zf-PARP; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region

    2. NM_180255.3 → NP_850586.2  phosphoesterase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850586.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F8L1
      Conserved Domains (3) summary
      cd01427
      Location:512 → 669
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      pfam00645
      Location:321 → 394
      zf-PARP; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
      pfam08645
      Location:511 → 675
      PNK3P; Polynucleotide kinase 3 phosphatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84JE8.1

    Gene LinkOut

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