CSI1 binding protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CSI1
Official Full Name: binding protein
Primary source: TAIR:AT2G22125
Locus tag: AT2G22125
See related: Araport:AT2G22125
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: cellulose synthase-interactive protein 1; POM-POM 2; POM2; T16B14.2
Summary: Encodes a protein involved in cell elongation in root and anther filaments. Mutants have greater cell volumes in root tissues and have additive phenotypes with other cell expansion mutants such as those carrying mutations in COB, QUI and POM1 loci. POM2/CSI1 promotes Cellulose Synthase and microtubule co-alignment.
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Genomic context

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See CSI1 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 8

Sequence:: Chromosome: 2; NC_003071.7 (9406059..9414578)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cellulose synthase interactive1- and microtubule-dependent cell wall architecture is required for acid growth in Arabidopsis hypocotyls.
Title: Cellulose synthase interactive1- and microtubule-dependent cell wall architecture is required for acid growth in Arabidopsis hypocotyls.
Small CESA compartments (SmaCCs) or microtubule-associated cellulose synthase compartments (MASCs) are critical for fast recovery of CSCs to the plasma membrane after stress is relieved in Arabidopsis thaliana. This SmaCC/MASC-mediated fast recovery of CSCs is dependent on CELLULOSE SYNTHASE INTERACTIVE1 (CSI1), a protein previously known to represent the link between CSCs and cortical microtubules.
Title: CELLULOSE SYNTHASE INTERACTIVE1 Is Required for Fast Recycling of Cellulose Synthase Complexes to the Plasma Membrane in Arabidopsis.
the sustained cellulose synthesis is important for salt stress tolerance in Arabidopsis.
Title: Cellulose synthesis genes CESA6 and CSI1 are important for salt stress tolerance in Arabidopsis.
CSI1 and the COMPANIONS OF CELLULOSE SYNTHASE proteins fulfil distinct functions during cellulose synthesis.
Title: The cellulose synthase companion proteins act non-redundantly with CELLULOSE SYNTHASE INTERACTING1/POM2 and CELLULOSE SYNTHASE 6.
The Cellulose synthase complex (CSC)-associated proteins KORRIGAN1 (KOR1) and POM2/CELLULOSE SYNTHASE INTERACTIVE PROTEIN1 (CSI1) were differentially affected by CESTRIN treatment, indicating different forms of association with the plasma membrane CSCs.
Title: CESA TRAFFICKING INHIBITOR inhibits cellulose deposition and interferes with the trafficking of cellulose synthase complexes and their associated proteins KORRIGAN1 and POM2/CELLULOSE SYNTHASE INTERACTIVE PROTEIN1.
CSI1 directly mediates the interaction between cellulose synthase complexes and microtubules.
Title: Cellulose synthase interactive protein 1 (CSI1) mediates the intimate relationship between cellulose microfibrils and cortical microtubules.
CSI1 is important for anther development by regulating microtubule stability and cell morphogenesis.
Title: The Arabidopsis ARCP protein, CSI1, which is required for microtubule stability, is necessary for root and anther development.
Data propose that POM2/CSI1 provides a scaffold between the cellulose synthases and cortical microtubules that guide cellulose synthesis.
Title: POM-POM2/cellulose synthase interacting1 is essential for the functional association of cellulose synthase and microtubules in Arabidopsis.
CESA interactive protein 1 (CSI1) is a microtubule-associated protein that bridges CESA complexes and cortical microtubules.
Title: Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes.
CSI1 interacts with cellulose synthase (CESA) isoforms involved in primary plant cell wall synthesis. Mutations in CSI1 cause defective cell elongation in hypocotyls and roots and reduce cellulose content. [CSI-1]
Title: Identification of a cellulose synthase-associated protein required for cellulose biosynthesis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_127781.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables microtubule binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within anisotropic cell growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in anisotropic cell growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in anther dehiscence	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cellulose biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellulose biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellulose microfibril organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cortical microtubule organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in gynoecium development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in plant-type primary cell wall biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pollen tube development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pollen wall assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to cortical microtubule cytoskeleton	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of cellulose biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in regulation of microtubule cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of root morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to calcium ion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
part_of cellulose synthase complex	IDA Inferred from Direct Assay more info	PubMed
part_of cellulose synthase complex	IMP Inferred from Mutant Phenotype more info	PubMed
located_in cortical microtubule	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasmic side of plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in microtubule minus-end	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plasma membrane	HDA more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasmodesma	HDA more info	PubMed

General protein information

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Preferred Names: binding protein

NP_179803.4

binding; FUNCTIONS IN: binding; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), Armadillo-like helical (InterPro:IPR011989), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Armadillo/beta-catenin-like repeat; C2 calcium/lipid-binding domain (CaLB) protein (TAIR:AT1G77460.2); Has 7763 Blast hits to 3084 proteins in 288 species: Archae - 8; Bacteria - 60; Metazoa - 1765; Fungi - 937; Plants - 4329; Viruses - 0; Other Eukaryotes - 664 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

9406059..9414578

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_127781.5 → NP_179803.4 binding protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_179803.4

Status: REVIEWED

UniProtKB/Swiss-Prot

F4IIM1, Q0WUD1, Q6NPD6, Q8RUY6

UniProtKB/TrEMBL

A0A178VZS4

Conserved Domains (5) summary

PLN03200
Location:49 → 2150

PLN03200; cellulose synthase-interactive protein; Provisional

cd00020
Location:530 → 685

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam00168
Location:2030 → 2130

C2; C2 domain

sd00044
Location:83 → 104

HEAT; HEAT repeat [structural motif]

sd00043
Location:528 → 564

ARM; armadillo repeat [structural motif]