U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MYA1 myosin 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838333, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MYA1
    Official Full Name
    myosin 1
    Primary source
    TAIR:AT1G17580
    Locus tag
    AT1G17580
    See related
    Araport:AT1G17580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS MYOSIN 1; ATMYA1; F1L3.28; F1L3_28; myosin 1; MYOSIN XI 1; XI-1
    Summary
    Encodes a member of the type XI myosin protein family involved in organelle trafficking and overall plant development.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MYA1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    38
    Sequence:
    Chromosome: 1; NC_003070.9 (6039250..6049685)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene tRNA-Ser Neighboring gene Ribosomal protein L14p/L23e family protein Neighboring gene nuclear factor Y, subunit A8 Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Disease resistance protein (TIR-NBS class)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Inter-dependence of dimerization and organelle binding in myosin XI. Li JF, et al. Plant J, 2008 Aug. PMID 18429938
    2. Enzymatic activity and motility of recombinant Arabidopsis myosin XI, MYA1. Hachikubo Y, et al. Plant Cell Physiol, 2007 Jun. PMID 17504816
    3. Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis. Ojangu EL, et al. BMC Plant Biol, 2012 Jun 6. PMID 22672737, Free PMC Article
    4. Myosins XI modulate host cellular responses and penetration resistance to fungal pathogens. Yang L, et al. Proc Natl Acad Sci U S A, 2014 Sep 23. PMID 25201952, Free PMC Article
    5. Overlapping functions of the four class XI myosins in Arabidopsis growth, root hair elongation, and organelle motility. Prokhnevsky AI, et al. Proc Natl Acad Sci U S A, 2008 Dec 16. PMID 19060218, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. findings establish myosins XI as key regulators of plant antifungal immunity.
      Title: Myosins XI modulate host cellular responses and penetration resistance to fungal pathogens.
    2. The class XI myosins XI-K, XI-1 and XI-2 have partially redundant roles in the growth of shoot epidermis. Myosin XI-K plays more important role whereas myosins XI-1 and XI-2 have minor roles in the determination of size and shape of epidermal cells.
      Title: Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis.
    3. There is an inter-dependent relationship between dimerization and organelle binding in MYA1, whereby each process synergistically stimulates the other.
      Title: Inter-dependence of dimerization and organelle binding in myosin XI.
    4. results strongly suggest that MYA1 is a processive motor and involved in vesicle transport and/or cytoplasmic streaming
      Title: Enzymatic activity and motility of recombinant Arabidopsis myosin XI, MYA1.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_101620.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cytoskeletal motor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within actin filament-based movement TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within cell division IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within fruit development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within gynoecium development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf pavement cell development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within mitochondrion localization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within peroxisome localization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within post-embryonic development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within trichome morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    myosin 1
    NP_173201.2
    • myosin 1 (MYA1); FUNCTIONS IN: motor activity; INVOLVED IN: in 8 processes; LOCATED IN: myosin complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dil domain (InterPro:IPR018444), Dilute (InterPro:IPR002710), Myosin, N-terminal, SH3-like (InterPro:IPR004009), Myosin head, motor domain (InterPro:IPR001609), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: Myosin family protein with Dil domain (TAIR:AT5G20490.1); Has 18995 Blast hits to 13821 proteins in 1312 species: Archae - 114; Bacteria - 980; Metazoa - 11844; Fungi - 1348; Plants - 1046; Viruses - 13; Other Eukaryotes - 3650 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6039250..6049685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101620.3 → NP_173201.2  myosin 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173201.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39160, Q9LNP7
      UniProtKB/TrEMBL
      A0A5S9UVU5, A0A654EAK7
      Conserved Domains (5) summary
      smart00015
      Location:850 → 872
      IQ; Calmodulin-binding motif
      COG1196
      Location:867 → 1114
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd15475
      Location:1099 → 1486
      MyosinXI_CBD; cargo binding domain of myosin XI
      cd01384
      Location:73 → 717
      MYSc_Myo11; class XI myosin, motor domain
      pfam02736
      Location:9 → 47
      Myosin_N; Myosin N-terminal SH3-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39160.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools