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    CG11334 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43713, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11334provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039849
    Locus tag
    Dmel_CG11334
    See related
    AllianceGenome:FB:FBgn0039849
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11334
    Summary
    Predicted to enable S-methyl-5-thioribose-1-phosphate isomerase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Is expressed in adult head; embryonic/larval midgut; gastric caecum; and organism. Orthologous to human MRI1 (methylthioribose-1-phosphate isomerase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11334 in Genome Data Viewer
    Location:
    100C4-100C4; 3-102 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31459822..31463037, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27285544..27288759, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Gcn2 Neighboring gene Polynucleotide phosphorylase Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene Lysyl oxidase-like 1 Neighboring gene long non-coding RNA:CR45554 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Moesin is a major regulator of centrosome behavior in epithelial cells with extra centrosomes. Sabino D, et al. Curr Biol, 2015 Mar 30. PMID 25772448, Free PMC Article
    2. Regulation of smoothened by Drosophila G-protein-coupled receptor kinases. Cheng S, et al. Dev Biol, 2010 Jan 1. PMID 19850026, Free PMC Article
    3. Quantitative evolutionary genomics: differential gene expression and male reproductive success in Drosophila melanogaster. Drnevich JM, et al. Proc Biol Sci, 2004 Nov 7. PMID 15539352, Free PMC Article
    4. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Parkhitko AA, et al. Genes Dev, 2016 Jun 15. PMID 27313316, Free PMC Article
    5. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables S-methyl-5-thioribose-1-phosphate isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-methionine salvage from methylthioadenosine IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11334-PA
    CG11334-PB
    CG11334-PC
    NP_001263144.1
    NP_651868.1
    NP_733430.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31459822..31463037 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170551.3 → NP_733430.1  uncharacterized protein Dmel_CG11334, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733430.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V9X4
      UniProtKB/TrEMBL
      A0A0B4KI38
      Related
      FBpp0085169
      Conserved Domains (2) summary
      TIGR00512
      Location:4 → 351
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:44 → 351
      IF-2B; Initiation factor 2 subunit family

    2. NM_001276215.1 → NP_001263144.1  uncharacterized protein Dmel_CG11334, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263144.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V9X4
      UniProtKB/TrEMBL
      A0A0B4KI38
      Conserved Domains (2) summary
      TIGR00512
      Location:4 → 351
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:44 → 351
      IF-2B; Initiation factor 2 subunit family

    3. NM_143611.3 → NP_651868.1  uncharacterized protein Dmel_CG11334, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651868.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V9X4
      UniProtKB/TrEMBL
      A0A0B4KI38
      Related
      FBpp0085170
      Conserved Domains (2) summary
      TIGR00512
      Location:4 → 351
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:44 → 351
      IF-2B; Initiation factor 2 subunit family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KI38 A0A0B4KI38
    Q9V9X4.1 Q9V9X4

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