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    MFS17 Major Facilitator Superfamily Transporter 17 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3354861, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MFS17provided by FlyBase
    Official Full Name
    Major Facilitator Superfamily Transporter 17provided by FlyBase
    Primary source
    FLYBASE:FBgn0058263
    Locus tag
    Dmel_CG40263
    See related
    AllianceGenome:FB:FBgn0058263
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD07241; bs24e02.y1; CG40263; Dmel\CG40263
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See MFS17 in Genome Data Viewer
    Location:
    41A1-41A1; 2-55 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (2494742..2565385, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2RHet NW_001848856.1 (1265405..1336048, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46487 Neighboring gene pseudo Neighboring gene mir-2279 stem loop Neighboring gene long non-coding RNA:CR46481 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HP1a targets the Drosophila KDM4A demethylase to a subset of heterochromatic genes to regulate H3K36me3 levels. Lin CH, et al. PLoS One, 2012. PMID 22761891, Free PMC Article
    2. Genome ARTIST_v2-An Autonomous Bioinformatics Tool for Annotation of Natural Transposons in Sequenced Genomes. Ecovoiu AA, et al. Int J Mol Sci, 2022 Oct 21. PMID 36293549, Free PMC Article
    3. Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins. Kramer MC, et al. Genes Dev, 2015 Oct 15. PMID 26450910, Free PMC Article
    4. Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Roignant JY, et al. Cell, 2010 Oct 15. PMID 20946982, Free PMC Article
    5. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org
    • mir-2279-RA; Dmel\mir-2279-RA; CR42911-RA; Dmel\CR42911-RA
    • mir-2279-RB; Dmel\mir-2279-RB; CR42911-RB; Dmel\CR42911-RB

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    major facilitator superfamily transporter 17
    Names
    CG40263-PF
    CG40263-PG
    CG40263-PH
    CG40263-PI
    CG40263-PJ
    MFS17-PF
    MFS17-PG
    MFS17-PH
    MFS17-PI
    MFS17-PJ

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      2494742..2565385 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001110894.2 → NP_001104364.2  major facilitator superfamily transporter 17, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001104364.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0C4DHN3

    2. NM_001015096.4 → NP_001015096.2  major facilitator superfamily transporter 17, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015096.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8Y4X9, Q494G7, Q8IH77
      Conserved Domains (2) summary
      cd06174
      Location:41 → 467
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:34 → 477
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

    3. NM_001276229.1 → NP_001263158.1  major facilitator superfamily transporter 17, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263158.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0C4DHN7, Q8IH77
      Conserved Domains (1) summary
      cd06174
      Location:41 → 438
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    4. NM_001110895.3 → NP_001104365.2  major facilitator superfamily transporter 17, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001104365.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8Y4X9, Q494G7, Q8IH77
      Conserved Domains (2) summary
      cd06174
      Location:41 → 467
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:34 → 477
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

    5. NM_001015095.4 → NP_001015095.1  major facilitator superfamily transporter 17, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001015095.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7PLD0, Q8IH77
      Conserved Domains (2) summary
      cd06174
      Location:41 → 438
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:34 → 443
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0C4DHN3 A0A0C4DHN3
    A0A0C4DHN7 A0A0C4DHN7
    Q494G7 Q494G7
    Q7PLD0 Q7PLD0
    Q8IH77 Q8IH77

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