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    CG3434 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39098, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3434provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036000
    Locus tag
    Dmel_CG3434
    See related
    AllianceGenome:FB:FBgn0036000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3434
    Summary
    Predicted to enable pentosyltransferase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to be part of tRNA-guanine transglycosylase complex. Is expressed in several structures, including Malpighian tubule primordium; dorsal pharyngeal muscle cell; embryonic/larval midgut; embryonic/larval midgut primordium; and mesoderm. Orthologous to human QTRT2 (queuine tRNA-ribosyltransferase accessory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3434 in Genome Data Viewer
    Location:
    67B8-67B8; 3-29 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9459369..9460799, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9452469..9453899, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pleiohomeotic like Neighboring gene antisense RNA:CR45873 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ubiquitin carboxy-terminal hydrolase L5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. H/ACA snRNP-dependent ribosome biogenesis regulates translation of polyglutamine proteins. Breznak SM, et al. Sci Adv, 2023 Jun 23. PMID 37343092, Free PMC Article
    2. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Orian A, et al. Genes Dev, 2003 May 1. PMID 12695332, Free PMC Article
    3. Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Schertel C, et al. Dev Cell, 2013 Apr 29. PMID 23583758
    4. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624
    5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables pentosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA-guanine transglycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA-guanine transglycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA-guanine transglycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic side of mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of tRNA-guanine transglycosylase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3434-PA
    NP_648320.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9459369..9460799 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140063.5 → NP_648320.1  uncharacterized protein Dmel_CG3434 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648320.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VSZ6
      Related
      FBpp0076201
      Conserved Domains (1) summary
      pfam01702
      Location:139 → 382
      TGT; Queuine tRNA-ribosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSZ6.1 Q9VSZ6

    Gene LinkOut

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