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    THA1 threonine aldolase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837385, updated on 18-Sep-2024

    Summary

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    Official Symbol
    THA1
    Official Full Name
    threonine aldolase 1
    Primary source
    TAIR:AT1G08630
    Locus tag
    AT1G08630
    See related
    Araport:AT1G08630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F22O13.11; F22O13_11; threonine aldolase 1
    Summary
    Encodes a threonine aldolase, involved in threonine degradation to glycine. Primarily expressed in seeds and seedlings.
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    Genomic context

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    See THA1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (2743761..2747967, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene ncRNA Neighboring gene Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein Neighboring gene Chloroplast J-like domain 1 Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene phosphoenolpyruvate carboxylase kinase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two Arabidopsis threonine aldolases are nonredundant and compete with threonine deaminase for a common substrate pool. Joshi V, et al. Plant Cell, 2006 Dec. PMID 17172352, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001035924.2
    NM_001084023.1
    NM_001331780.1
    NM_001331781.1
    NM_100736.3
    NM_179283.2
    NM_179284.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables threonine aldolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within threonine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    threonine aldolase 1
    NP_001077492.1
    • threonine aldolase 1 (THA1); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aromatic amino acid beta-eliminating lyase/threonine aldolase (InterPro:IPR001597), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: threonine aldolase 2 (TAIR:AT3G04520.2); Has 3797 Blast hits to 3793 proteins in 1149 species: Archae - 25; Bacteria - 2286; Metazoa - 91; Fungi - 253; Plants - 87; Viruses - 0; Other Eukaryotes - 1055 (source: NCBI BLink).
    NP_001318956.1
    • threonine aldolase 1 (THA1); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aromatic amino acid beta-eliminating lyase/threonine aldolase (InterPro:IPR001597), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: threonine aldolase 2 (TAIR:AT3G04520.1); Has 4107 Blast hits to 4101 proteins in 1235 species: Archae - 29; Bacteria - 2521; Metazoa - 93; Fungi - 250; Plants - 87; Viruses - 0; Other Eukaryotes - 1127 (source: NCBI BLink).
    NP_563822.1
    • threonine aldolase 1 (THA1); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aromatic amino acid beta-eliminating lyase/threonine aldolase (InterPro:IPR001597), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: threonine aldolase 2 (TAIR:AT3G04520.1); Has 4107 Blast hits to 4101 proteins in 1235 species: Archae - 29; Bacteria - 2521; Metazoa - 93; Fungi - 250; Plants - 87; Viruses - 0; Other Eukaryotes - 1127 (source: NCBI BLink).
    NP_849614.1
    • threonine aldolase 1 (THA1); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aromatic amino acid beta-eliminating lyase/threonine aldolase (InterPro:IPR001597), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: threonine aldolase 2 (TAIR:AT3G04520.1); Has 4107 Blast hits to 4101 proteins in 1235 species: Archae - 29; Bacteria - 2521; Metazoa - 93; Fungi - 250; Plants - 87; Viruses - 0; Other Eukaryotes - 1127 (source: NCBI BLink).
    NP_849615.1
    • threonine aldolase 1 (THA1); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aromatic amino acid beta-eliminating lyase/threonine aldolase (InterPro:IPR001597), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: threonine aldolase 2 (TAIR:AT3G04520.1); Has 4107 Blast hits to 4101 proteins in 1235 species: Archae - 29; Bacteria - 2521; Metazoa - 93; Fungi - 250; Plants - 87; Viruses - 0; Other Eukaryotes - 1127 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2743761..2747967 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084023.1 → NP_001077492.1  threonine aldolase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077492.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W3I7
      Conserved Domains (1) summary
      PLN02721
      Location:1 → 338
      PLN02721; threonine aldolase

    2. NM_179283.2 → NP_849614.1  threonine aldolase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849614.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG61, Q2V4P5, Q8LC88, Q8RXU4, Q9FRS2
      UniProtKB/TrEMBL
      A0A178W3I7, A0A654E972
      Conserved Domains (1) summary
      PLN02721
      Location:1 → 352
      PLN02721; threonine aldolase

    3. NM_001331781.1 → NP_001322023.1  threonine aldolase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W3I7, A0A1P8ASQ3

    4. NM_001035924.2 → NP_001031001.2  threonine aldolase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031001.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG61, Q2V4P5, Q8LC88, Q8RXU4, Q9FRS2
      UniProtKB/TrEMBL
      A0A178W3I7, A0A654E972
      Conserved Domains (1) summary
      PLN02721
      Location:1 → 352
      PLN02721; threonine aldolase

    5. NM_100736.3 → NP_563822.1  threonine aldolase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563822.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG61, Q2V4P5, Q8LC88, Q8RXU4, Q9FRS2
      UniProtKB/TrEMBL
      A0A178W3I7, A0A654E972
      Conserved Domains (1) summary
      PLN02721
      Location:1 → 352
      PLN02721; threonine aldolase

    6. NM_179284.4 → NP_849615.1  threonine aldolase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849615.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG61, Q2V4P5, Q8LC88, Q8RXU4, Q9FRS2
      UniProtKB/TrEMBL
      A0A178W3I7, A0A654E972
      Conserved Domains (1) summary
      PLN02721
      Location:1 → 352
      PLN02721; threonine aldolase

    7. NM_001331780.1 → NP_001318956.1  threonine aldolase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG61, Q2V4P5, Q8LC88, Q8RXU4, Q9FRS2
      UniProtKB/TrEMBL
      A0A178W3I7, A0A654E972
      Conserved Domains (1) summary
      PLN02721
      Location:1 → 352
      PLN02721; threonine aldolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RXU4.1

    Gene LinkOut

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