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    LEW1 Undecaprenyl pyrophosphate synthetase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 5007686, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LEW1
    Official Full Name
    Undecaprenyl pyrophosphate synthetase family protein
    Primary source
    TAIR:AT1G11755
    Locus tag
    AT1G11755
    See related
    Araport:AT1G11755
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    LEAF WILTING 1
    Summary
    Encodes a cis-prenyltransferase, involved in dolichol biosynthesis. Wilted leaves in mutants due to cell membrane lesions. Mutants have increased drought tolerance, but hypersensitve to dark stress.
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    Genomic context

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    See LEW1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (3969681..3971911, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ankyrin repeat family protein Neighboring gene ncRNA Neighboring gene CLP protease proteolytic subunit 6 Neighboring gene mediator of RNA polymerase II transcription subunit-like protein Neighboring gene Plant self-incompatibility protein S1 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dolichol biosynthesis and its effects on the unfolded protein response and abiotic stress resistance in Arabidopsis. Zhang H, et al. Plant Cell, 2008 Jul. PMID 18612099, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001084049.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables dehydrodolichyl diphosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within dolichol biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein N-linked glycosylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to low light intensity stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of dehydrodolichyl diphosphate synthase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Undecaprenyl pyrophosphate synthetase family protein
    NP_001077518.1
    • LEAF WILTING 1 (LEW1); CONTAINS InterPro DOMAIN/s: Di-trans-poly-cis-decaprenylcistransferase-like (InterPro:IPR001441); Has 155 Blast hits to 155 proteins in 74 species: Archae - 0; Bacteria - 0; Metazoa - 62; Fungi - 51; Plants - 42; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3969681..3971911 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084049.2 → NP_001077518.1  Undecaprenyl pyrophosphate synthetase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077518.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W879, A0A5S9TXD2, Q8H0V2
    Nucleotide Protein
    Heading Accession and Version

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